• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

绝缘子蛋白Su(Hw)在卵子发生早期对果蝇卵泡细胞（DAFCs）中部分扩增子的扩增不可或缺。

Insulator Protein Su(Hw) Is Indispensable for Amplification of Part of Drosophila Amplicons in Follicular Cells (DAFCs) during Early Oogenesis.

作者信息

Krasnov A N, Vorobyova N E, Mazina M Yu

机构信息

Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia.

出版信息

Dokl Biochem Biophys. 2018 Mar;479(1):80-82. doi: 10.1134/S1607672918020059. Epub 2018 May 19.

DOI:10.1134/S1607672918020059
PMID:29779102
Abstract

We found that the Su(Hw) insulator protein binds to all known Drosophila amplicons in follicular cells (DAFCs). Su(Hw) binding is required for ORC replication complex positioning on part of DAFCs during early oogenesis. Our data allow us to expand the current view on the role of the Su(Hw) protein in Drosophila oogenesis as a transcription repressor. We assume that Su(Hw) is involved in the coordination of transcription and replication processes during oogenesis in Drosophila.

摘要

我们发现，抑制子（Su(Hw)）绝缘子蛋白与卵泡细胞（DAFCs）中所有已知的果蝇扩增子结合。在卵子发生早期，ORC复制复合体定位于部分DAFCs上需要Su(Hw)的结合。我们的数据使我们能够拓展目前关于Su(Hw)蛋白在果蝇卵子发生中作为转录抑制因子的作用的观点。我们推测，Su(Hw)参与了果蝇卵子发生过程中转录和复制过程的协调。

相似文献

1
Insulator Protein Su(Hw) Is Indispensable for Amplification of Part of Drosophila Amplicons in Follicular Cells (DAFCs) during Early Oogenesis.绝缘子蛋白Su(Hw)在卵子发生早期对果蝇卵泡细胞（DAFCs）中部分扩增子的扩增不可或缺。
Dokl Biochem Biophys. 2018 Mar;479(1):80-82. doi: 10.1134/S1607672918020059. Epub 2018 May 19.
2
Su(Hw) primes 66D and 7F Drosophila chorion genes loci for amplification through chromatin decondensation.Su(Hw) 通过染色质去凝聚引发 66D 和 7F 果蝇卵壳基因座的扩增。
Sci Rep. 2021 Aug 20;11(1):16963. doi: 10.1038/s41598-021-96488-0.
3
The insulator protein Suppressor of Hairy wing is required for proper ring canal development during oogenesis in Drosophila.在果蝇卵子发生过程中，绝缘子蛋白“毛翅抑制因子”是正常环管发育所必需的。
Dev Biol. 2015 Jul 1;403(1):57-68. doi: 10.1016/j.ydbio.2015.03.024. Epub 2015 Apr 14.
4
The role of the Suppressor of Hairy-wing insulator protein in Drosophila oogenesis.抑制毛翅绝缘子蛋白在果蝇卵子发生中的作用。
Dev Biol. 2011 Aug 15;356(2):398-410. doi: 10.1016/j.ydbio.2011.05.666. Epub 2011 May 30.
5
The insulator protein Suppressor of Hairy-wing is an essential transcriptional repressor in the Drosophila ovary.绝缘子蛋白 Suppressor of Hairy-wing 是果蝇卵巢中必需的转录抑制因子。
Development. 2013 Sep;140(17):3613-23. doi: 10.1242/dev.094953. Epub 2013 Jul 24.
6
[The Role of Su(Hw) Protein in Transcription Regulation in Drosophila melanogaster].[Su(Hw)蛋白在黑腹果蝇转录调控中的作用]
Genetika. 2015 Nov;51(11):1234-43.
7
[Ability of Su(Hw) to create a platform for ORC binding does not depend on the type of surrounding chromatin].[Su(Hw) 创建 ORC 结合平台的能力不依赖于周围染色质的类型]
Tsitologiia. 2013;55(4):218-24.
8
HIPP1 stabilizes the interaction between CP190 and Su(Hw) in the Drosophila insulator complex.HIPP1 稳定了果蝇绝缘子复合物中 CP190 和 Su(Hw)之间的相互作用。
Sci Rep. 2019 Dec 13;9(1):19102. doi: 10.1038/s41598-019-55617-6.
9
Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome.绝缘子蛋白 Su(Hw) 招募 SAGA 和 Brahma 复合物，并构成果蝇基因组中识别复合物结合位点的一部分。
Nucleic Acids Res. 2013 Jun;41(11):5717-30. doi: 10.1093/nar/gkt297. Epub 2013 Apr 22.
10
A transcriptional insulator element, the su(Hw) binding site, protects a chromosomal DNA replication origin from position effects.一种转录绝缘子元件，即su(Hw)结合位点，可保护染色体DNA复制起点免受位置效应的影响。
Mol Cell Biol. 1997 Apr;17(4):2202-6. doi: 10.1128/MCB.17.4.2202.

引用本文的文献

1
Su(Hw) primes 66D and 7F Drosophila chorion genes loci for amplification through chromatin decondensation.Su(Hw) 通过染色质去凝聚引发 66D 和 7F 果蝇卵壳基因座的扩增。
Sci Rep. 2021 Aug 20;11(1):16963. doi: 10.1038/s41598-021-96488-0.
2
Zinc Finger Protein CG9890 - New Component of ENY2-Containing Complexes of Drosophila.锌指蛋白CG9890——果蝇含ENY2复合体的新组分。
Acta Naturae. 2018 Oct-Dec;10(4):110-114.

本文引用的文献

1
The insulator protein Suppressor of Hairy-wing is an essential transcriptional repressor in the Drosophila ovary.绝缘子蛋白 Suppressor of Hairy-wing 是果蝇卵巢中必需的转录抑制因子。
Development. 2013 Sep;140(17):3613-23. doi: 10.1242/dev.094953. Epub 2013 Jul 24.
2
[Ability of Su(Hw) to create a platform for ORC binding does not depend on the type of surrounding chromatin].[Su(Hw) 创建 ORC 结合平台的能力不依赖于周围染色质的类型]
Tsitologiia. 2013;55(4):218-24.
3
Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome.
绝缘子蛋白 Su(Hw) 招募 SAGA 和 Brahma 复合物，并构成果蝇基因组中识别复合物结合位点的一部分。
Nucleic Acids Res. 2013 Jun;41(11):5717-30. doi: 10.1093/nar/gkt297. Epub 2013 Apr 22.
4
Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression.果蝇滤泡细胞基因扩增的综合分析：起始激活和抑制的参数。
Genes Dev. 2011 Jul 1;25(13):1384-98. doi: 10.1101/gad.2043111.
5
The role of the Suppressor of Hairy-wing insulator protein in Drosophila oogenesis.抑制毛翅绝缘子蛋白在果蝇卵子发生中的作用。
Dev Biol. 2011 Aug 15;356(2):398-410. doi: 10.1016/j.ydbio.2011.05.666. Epub 2011 May 30.
6
Chromatin insulators.染色质绝缘子
Annu Rev Genet. 2006;40:107-38. doi: 10.1146/annurev.genet.39.073003.113546.