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[涎腺腺样囊性癌神经侵犯分子机制的研究进展]

[Advances in the molecular mechanisms of perineural invasion in salivary adenoid cystic carcinoma].

作者信息

Zhang Mei, Liang Xin-Hua, Tang Ya-Ling

机构信息

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Apr 1;36(2):204-211. doi: 10.7518/hxkq.2018.02.017.

Abstract

Salivary adenoid cystic carcinoma is a very common malignant neoplasm in the salivary glands. One of the most important features of salivary cystic carcinoma is perineural invasion, which renders its complete removal is very difficult through clinical surgery. Consequently, tumor recurrence occurs easily after clinical surgery. Therefore, the molecular mechanisms of perineural invasion in salivary adenoid cystic carcinoma are necessary to explore. These mechanisms are reviewed in this paper.

摘要

涎腺腺样囊性癌是涎腺中一种非常常见的恶性肿瘤。涎腺囊性癌最重要的特征之一是神经侵犯,这使得通过临床手术将其完全切除非常困难。因此,临床手术后肿瘤很容易复发。所以,有必要探索涎腺腺样囊性癌神经侵犯的分子机制。本文对这些机制进行了综述。

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本文引用的文献

1
Mechanisms of cancer dissemination along nerves.癌症沿神经扩散的机制。
Nat Rev Cancer. 2016 Jun;16(6):399-408. doi: 10.1038/nrc.2016.38. Epub 2016 May 6.

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