Department of Medicine, The Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; Rehabilitation Research & Development Center of Excellence for the Medical Consequences of Spinal Cord Injury, The James J. Peters VAMC, 130 West Kingsbridge Road, Bronx, NY 10468, USA.
Department of Medicine, The Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA; Rehabilitation Research & Development Center of Excellence for the Medical Consequences of Spinal Cord Injury, The James J. Peters VAMC, 130 West Kingsbridge Road, Bronx, NY 10468, USA; Department of Rehabilitation Medicine, The Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, New York, NY 10029, USA.
Clin Chest Med. 2018 Jun;39(2):411-425. doi: 10.1016/j.ccm.2018.02.002.
In the United States, approximately 17,500 cases of traumatic spinal cord injury (SCI) occur each year, with an estimated 245,000 to 345,000 individuals living with chronic SCI. Acute management of respiratory dysfunction has resulted in improvement in early survival, but life expectancy remains less than that of the general population, and pulmonary complications are a leading cause of mortality. The global changes in pulmonary function, underlying pathophysiology, and the management options to improve respiratory muscle weakness and pulmonary clearance in persons with SCI are discussed. Given its high prevalence among subjects with cervical SCI, sleep disordered breathing is also discussed.
在美国，每年大约有 17500 例创伤性脊髓损伤 (SCI) 发生，估计有 245000 至 345000 人患有慢性 SCI。对呼吸功能障碍的急性处理导致早期存活率提高，但预期寿命仍低于一般人群，肺部并发症是导致死亡的主要原因。本文讨论了 SCI 患者的肺功能、潜在病理生理学以及改善呼吸肌无力和肺部清除功能的管理选择的全球变化。鉴于颈椎 SCI 患者中这种疾病的高患病率，本文还讨论了睡眠呼吸障碍紊乱。
