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[口腔鳞状癌的间质光动力疗法]

[Interstitial photodynamic therapy of oral squamous cancers].

作者信息

Wang K H

机构信息

Cancer Research Centre, Xiamen University.

出版信息

Zhonghua Zhong Liu Za Zhi. 1988 Nov;10(6):473-5.

PMID:2977974
Abstract

Photodynamic therapy (PDT) was studied in the treatment of a variety of solid malignant tumors. Ten patients with oral squamous cancers treated by PDT are reported: The laser beam was introduced into the malignant and metastatic lymphatic tissues through inserted optic fibers. The results showed that all the lesions gave complete response to PDT except the bony involvement. It was noted that the lymphatic metastatic foci showed a higher photosensitivity, and the covering skin, connective tissue and the nearby organs were not obviously injured. Combination of PDT with chemotherapy, radiotherapy and surgery are also discussed.

摘要

研究了光动力疗法(PDT)在治疗多种实体恶性肿瘤中的应用。报告了10例接受PDT治疗的口腔鳞状癌患者:通过插入的光纤将激光束引入恶性和转移性淋巴组织。结果显示,除骨受累外,所有病变对PDT均有完全反应。值得注意的是,淋巴转移灶显示出更高的光敏性,覆盖的皮肤、结缔组织和附近器官未受到明显损伤。还讨论了PDT与化疗、放疗和手术的联合应用。

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