Zsóri Gábor, Illés Dóra, Terzin Viktória, Ivány Emese, Czakó László
University of Szeged, Faculty of Medicine, Albert Szent-Györgyi Medical and Pharmaceutical Center, First Department of Medicine, Szeged, Korányi Fasor 8-10, H-6720, Hungary.
University of Szeged, Faculty of Medicine, Albert Szent-Györgyi Medical and Pharmaceutical Center, First Department of Medicine, Szeged, Korányi Fasor 8-10, H-6720, Hungary.
Pancreatology. 2018 Jul;18(5):559-565. doi: 10.1016/j.pan.2018.05.006. Epub 2018 May 18.
The exocrine and endocrine pancreata are very closely linked both anatomically and physiologically. Abdominal symptoms such as nausea, bloating, diarrhea, steatorrhea, and weight loss can often occur in diabetic patients. Impairments of the exocrine pancreatic function seem to be a frequent complication of diabetes mellitus; however, they are largely overlooked. The aim of this paper is to provide an overview of the current concepts of exocrine pancreatic insufficiency (PEI) in diabetes mellitus. The prevalence and symptoms of PEI in diabetes mellitus, the pathomechanism, and difficulties of diagnosis and therapy of PEI are summarized in this systematic review.
胰腺的外分泌部和内分泌部在解剖学和生理学上联系非常紧密。糖尿病患者常出现恶心、腹胀、腹泻、脂肪泻和体重减轻等腹部症状。胰腺外分泌功能受损似乎是糖尿病的常见并发症;然而,它们在很大程度上被忽视了。本文旨在概述糖尿病中外分泌性胰腺功能不全(PEI)的当前概念。本系统评价总结了糖尿病中PEI的患病率和症状、发病机制以及诊断和治疗的难点。