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索布拉烯,一种新的性聚集信息素,可能是紫杉二烯合酶级联反应的分流代谢产物,由白蛉物种复合体的一个成员产生。

Sobralene, a new sex-aggregation pheromone and likely shunt metabolite of the taxadiene synthase cascade, produced by a member of the sand fly species complex.

作者信息

Palframan Matthew J, Bandi Krishna K, Hamilton James G C, Pattenden Gerald

机构信息

School of Chemistry, The University of Nottingham, University Park, Nottingham NG7 2RD, UK.

Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YG, UK.

出版信息

Tetrahedron Lett. 2018 May 16;59(20):1921-1923. doi: 10.1016/j.tetlet.2018.03.088.

DOI:10.1016/j.tetlet.2018.03.088
PMID:29780183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5937913/
Abstract

A new sex-aggregation pheromone, sobralene, produced by the sand fly from Sobral (Ceará State, Brazil) is shown to have the novel 6,12-membered ring-fused diterpene structure It is proposed that sobralene is a likely shunt metabolite of the taxadiene synthase-catalysed cyclisation of geranygeranyl diphosphate.

摘要

一种由来自巴西塞阿拉州索布拉尔的白蛉产生的新型性聚集信息素——索布拉烯,被证明具有新颖的6,12-元环稠合二萜结构。有人提出,索布拉烯可能是香叶基香叶基二磷酸经紫杉二烯合酶催化环化反应的分流代谢产物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/4003cdbe3aec/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/69faa1a966fa/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/1d87d9fa623d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/f922eca520a1/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/2d2475b37e35/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/4003cdbe3aec/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/69faa1a966fa/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/1d87d9fa623d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/f922eca520a1/fx2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/2d2475b37e35/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0474/5937913/4003cdbe3aec/gr3.jpg

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本文引用的文献

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Engineering of Taxadiene Synthase for Improved Selectivity and Yield of a Key Taxol Biosynthetic Intermediate.
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4
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