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B型主动脉夹层:新视角

Type B aortic dissection: new perspectives.

作者信息

Schepens Marc A A M

机构信息

Department of Cardiac Surgery, AZ St. Jan, Brugge, Belgium.

出版信息

J Vis Surg. 2018 Apr 23;4:75. doi: 10.21037/jovs.2018.03.16. eCollection 2018.

Abstract

BACKGROUND

Stanford type B aortic dissection is one of the aortic catastrophes with a high mortality and morbidity that needs immediate or delayed treatment, either surgically or endovascularly. This comprehensive review article addresses the current status of open, endovascular and hybrid treatment options for type B aortic dissections with the focus on new therapeutic perspectives.

METHODS

Evaluation of currently available evidence based on randomized and registry data and personal experience.

RESULTS

All type B dissections require prompt medical treatment to prevent aortic rupture. Acute complicated dissections are nowadays treated by endografting to reroute blood flow into the true lumen and promote false lumen thrombosis and future aortic remodeling. In acute uncomplicated situations the position of endografting is less clear and should be further delineated; however, on the long run also in these situations endografting might be protective for future aortic catastrophes in certain patient categories. In the chronic dissection with aneurysm formation of the descending thoracic and/or thoracoabdominal aorta, especially in connective tissue disorders, open surgery offers nowadays the best immediate results with long durability. Thoracic endografting plays only a minor role in these circumstances but branched and fenestrated endografting are very promising techniques. Hybrid techniques can offer the solution for high risk patients that are not suitable for open surgery.

CONCLUSIONS

Emergent thoracic endografting is the golden standard for all complicated type B dissections while uncomplicated patients with high-risk features might benefit from endovascular repair. Open surgery is limited for chronic post dissection aneurysms. Aortic surveillance is of paramount importance in all situations.

摘要

背景

B型主动脉夹层是一种具有高死亡率和发病率的主动脉灾难性疾病,需要立即或延迟进行手术或血管腔内治疗。这篇综述文章探讨了B型主动脉夹层开放手术、血管腔内治疗和杂交治疗方案的现状,并重点关注新的治疗前景。

方法

基于随机对照试验、注册研究数据及个人经验对现有证据进行评估。

结果

所有B型夹层均需及时进行药物治疗以预防主动脉破裂。如今,急性复杂夹层通过植入血管内支架将血流改道进入真腔,促进假腔血栓形成及未来主动脉重塑。在急性非复杂情况下,血管内支架植入的地位尚不明晰,仍需进一步明确;然而,从长远来看,在某些患者群体中,血管内支架植入对预防未来主动脉灾难性事件可能具有保护作用。在慢性夹层合并降胸主动脉和/或胸腹主动脉瘤形成时,尤其是在结缔组织疾病患者中,开放手术目前能提供最佳的近期效果及长期耐久性。在这些情况下,胸段血管内支架植入仅起次要作用,但分支型和开窗型血管内支架植入是非常有前景的技术。杂交技术可为不适合开放手术的高危患者提供解决方案。

结论

急诊胸段血管内支架植入是所有复杂B型夹层的金标准,而具有高危特征的非复杂患者可能从血管腔内修复中获益。开放手术对慢性夹层后动脉瘤的治疗存在局限性。在所有情况下,主动脉监测至关重要。

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