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骨组织形态计量学

Bone Area Histomorphometry.

作者信息

Andronowski Janna M, Crowder Christian

机构信息

Department of Biology, The University of Akron, Akron, OH, 44325-3908.

Harris County Institute of Forensic Sciences, Houston, TX, 77030.

出版信息

J Forensic Sci. 2019 Mar;64(2):486-493. doi: 10.1111/1556-4029.13815. Epub 2018 May 21.

DOI:10.1111/1556-4029.13815
PMID:29783279
Abstract

Quantifying the amount of cortical bone loss is one variable used in histological methods of adult age estimation. Measurements of cortical area tend to be subjective and additional information regarding bone loss is not captured considering cancellous bone is disregarded. We describe whether measuring bone area (cancellous + cortical area) rather than cortical area may improve histological age estimation for the sixth rib. Mid-shaft rib cross-sections (n = 114) with a skewed sex distribution were analyzed. Ages range from 16 to 87 years. Variables included: total cross-sectional area, cortical area, bone area, relative bone area, relative cortical area, and endosteal area. Males have larger mean total cross-sectional area, bone area, and cortical area than females. Females display a larger mean endosteal area and greater mean relative measure values. Relative bone area significantly correlates with age. The relative bone area variable will provide researchers with a less subjective and more accurate measure than cortical area.

摘要

量化皮质骨丢失量是成人年龄估计组织学方法中使用的一个变量。皮质面积的测量往往具有主观性,并且由于松质骨被忽略,未获取到关于骨质流失的其他信息。我们描述了测量骨面积(松质骨+皮质骨面积)而非皮质面积是否可以改善第六肋骨的组织学年龄估计。分析了性别分布不均衡的中段肋骨横截面(n = 114)。年龄范围为16至87岁。变量包括:总横截面积、皮质面积、骨面积、相对骨面积、相对皮质面积和骨内膜面积。男性的平均总横截面积、骨面积和皮质面积大于女性。女性的平均骨内膜面积更大,平均相对测量值更高。相对骨面积与年龄显著相关。与皮质面积相比,相对骨面积变量将为研究人员提供一个主观性更低、更准确的测量方法。

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