Platt Darren
Amyris Biotechnologies, 5885 Hollis Street, Suite 100 Emeryville, CA 94608, USA.
Per Med. 2009 Nov;6(6):669-679. doi: 10.2217/pme.09.50.
Direct-to-consumer (DTC) genomics services enable consumers to gain access to their DNA sequence using research microarrays and curated genetic association literature. For a few hundred US dollars, consumers can compare their genotypes against current research results, including risk estimates for common diseases based on SNPs. The DTC companies are legally avoiding claims of medical utility but are assembling the components needed for genomic-based healthcare. They represent an early vision of what modern personalized medicine could become. This has resulted in some conflict between the research and regulatory communities and there are reasonable questions as to whether the science is sufficiently mature. The DTC providers are exploring and solving problems associated with communicating complex scientific data and have the potential to revolutionize research by organizing large communities efficiently using web technology.
直接面向消费者（DTC）的基因组学服务使消费者能够通过研究用微阵列和经过整理的基因关联文献来获取自己的DNA序列。只需几百美元，消费者就可以将自己的基因型与当前的研究结果进行比较，包括基于单核苷酸多态性（SNP）的常见疾病风险评估。DTC公司在法律上避免声称具有医疗效用，但正在组装基于基因组的医疗保健所需的组件。它们代表了现代个性化医疗未来可能的早期愿景。这导致了研究界与监管界之间的一些冲突，并且对于科学是否足够成熟也存在合理的疑问。DTC提供商正在探索并解决与传达复杂科学数据相关的问题，并且有潜力通过利用网络技术高效地组织大型群体来彻底改变研究。
