Maleszka R, Maleszka A
Przegl Dermatol. 1988 Nov-Dec;75(6):425-30.
The effects were studied in vitro of a score of various additives to toilet soaps on strains of Candida albicans isolated from patients. Their effect on the basic properties of toilet soaps was studied, determining foam production and the index of foam stability, and their resistance to high temperature was determined since in the process of production high temperature might reduce their effects on C. albicans. The strongest fungicidal effect was exerted in strongly alkaline soap solutions by Clotrimazole. Good effects were obtained also using Clioquinol, a derivative of 8-hydroxyquinoline. The results of these studies suggest that certain substances may be added for exerting a fungicidal effect in alkaline medium protecting thus against fungal infections.
研究了多种添加到香皂中的添加剂对从患者分离出的白色念珠菌菌株的体外作用。研究了它们对香皂基本性质的影响，测定了泡沫产生量和泡沫稳定性指数，并测定了它们对高温的耐受性，因为在生产过程中高温可能会降低它们对白色念珠菌的作用。克霉唑在强碱性肥皂溶液中具有最强的杀菌作用。使用8-羟基喹啉衍生物氯碘羟喹也取得了良好效果。这些研究结果表明，可以添加某些物质在碱性介质中发挥杀菌作用，从而预防真菌感染。
