Yang Junyu, Xu Yongqing, He Xiaoqing
Graduate Department of Kunming Medical University, Kunming Yunnan, 650032, P. R. China.
Department of Orthopedic Surgery, Kunming General Hospital of Chengdu Military Command, Kunming Yunnan, 650032, P. R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2016 Dec 8;30(12):1562-1566. doi: 10.7507/1002-1892.20160321.
To summarize the research and application progress of magnesium and magnesium alloys implants in the orthopedics.
The domestic and foreign related literature about the research progress and application of magnesium and magnesium alloys implants in the orthopedics was reviewed.
Currently approved and commonly used metallic implants in orthopedics include stainless steels, titanium alloys, and chromium alloys having many disadvantages of poor biocompatibility, mismatch with the biomechanical properties of the bone tissue, and need of second surgical procedure to remove. Compared with traditional implants, magnesium and magnesium alloys have biomechanical properties closer to natural bone tissue, and degradation, which have the potential to serve as new biocompatible and degradable implants. Although magnesium and magnesium alloy materials have their own advantages, but the degradation rate is still too fast and so on. At present, the research and development of medical magnesium and magnesium alloy materials are to improve their corrosion resistance and control the rate of degradation.
Magnesium and magnesium alloys have great potential as a implant material in the orthopedics, through further systematic and in-depth study, it is expected to become a new generation of degradation biological implant materials.
总结镁及镁合金植入物在骨科领域的研究与应用进展。
回顾国内外有关镁及镁合金植入物在骨科领域研究进展及应用的相关文献。
目前骨科领域获批并常用的金属植入物包括不锈钢、钛合金和铬合金，它们存在生物相容性差、与骨组织生物力学性能不匹配以及需要二次手术取出等诸多缺点。与传统植入物相比，镁及镁合金具有更接近天然骨组织的生物力学性能以及可降解性，有潜力成为新型生物相容性和可降解植入物。尽管镁及镁合金材料有自身优势，但降解速率仍然过快等。目前医用镁及镁合金材料的研发方向是提高其耐腐蚀性并控制降解速率。
镁及镁合金作为骨科植入材料具有巨大潜力，通过进一步系统深入研究，有望成为新一代可降解生物植入材料。
