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[儿童及成人癫痫持续状态]

[Status epilepticus in children and adults].

作者信息

Bjellvi Johan, Timby Niklas, Flink Roland

机构信息

Sahlgrenska universitetssjukhuset - Goteborg, Sweden - Neurosjukvården, Sahlgrenska Universitetssjukhuset Göteborg, Sweden.

Norrlands universitetssjukhus - Umea, Sweden Norrlands universitetssjukhus - Umea, Sweden.

出版信息

Lakartidningen. 2018 May 22;115:E4XY.

PMID:29786808
Abstract

Status epilepticus, a condition with prolonged or repeated seizures, is a common neurological emergency with significant morbidity and mortality. This text outlines the treatment and initial work-up for convulsive and non-convulsive status epilepticus in adults and children. The most serious form is convulsive (tonic-clonic) status epilepticus, which requires rapid treatment and work-up. Bensodiazepines are the preferred initial treatment, while antiepileptic drugs and anesthetics are added if seizures continue. For other forms of status epilepticus, the treatment depends on the type of seizures and the patient's general condition. Etiological work-up is essential in any case of status epilepticus. Effective treatment and work-up in status epilepticus requires a defined treatment protocol and multidisciplinary cooperation.

摘要

癫痫持续状态是一种发作持续或反复的病症,是常见的神经系统急症,具有较高的发病率和死亡率。本文概述了成人和儿童惊厥性和非惊厥性癫痫持续状态的治疗及初始检查。最严重的形式是惊厥性(强直阵挛性)癫痫持续状态,需要迅速治疗和检查。苯二氮䓬类药物是首选的初始治疗药物,若癫痫发作持续则加用抗癫痫药物和麻醉剂。对于其他形式的癫痫持续状态,治疗取决于癫痫发作类型和患者的一般状况。在任何癫痫持续状态病例中,病因检查都是必不可少的。癫痫持续状态的有效治疗和检查需要明确的治疗方案和多学科合作。

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[Status epilepticus in children and adults].[儿童及成人癫痫持续状态]
Lakartidningen. 2018 May 22;115:E4XY.
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Refractory generalised convulsive status epilepticus : a guide to treatment.难治性全面惊厥性癫痫持续状态:治疗指南
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Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.儿童急性强直阵挛性惊厥(包括惊厥性癫痫持续状态)的药物管理。
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Algorithm for the treatment of status epilepticus: an Australian perspective.癫痫持续状态的治疗算法:澳大利亚视角
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Overview: definitions and classifications of seizure emergencies.概述:癫痫发作紧急情况的定义和分类。
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Neurocritical care: status epilepticus review.神经重症监护:癫痫持续状态综述
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A multicentre randomised controlled trial of levetiracetam versus phenytoin for convulsive status epilepticus in children (protocol): Convulsive Status Epilepticus Paediatric Trial (ConSEPT) - a PREDICT study.左乙拉西坦与苯妥英钠治疗儿童惊厥性癫痫持续状态的多中心随机对照试验(方案):惊厥性癫痫持续状态儿科试验(ConSEPT)——一项预测性研究。
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Status epilepticus: emergency management.癫痫持续状态:紧急处理
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引用本文的文献

1
Changes of biochemical biomarkers in the serum of children with convulsion status epilepticus: a prospective study.惊厥性癫痫持续状态患儿血清中生化标志物的变化:一项前瞻性研究。
BMC Neurol. 2022 May 27;22(1):196. doi: 10.1186/s12883-022-02686-2.