文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Takata M, Denton K M, Woods R L, Anderson W P

Emily E. E. Stewart Renal Laboratory, Baker Medical Research Institute, Prahran, Victoria, Australia.

Clin Exp Pharmacol Physiol. 1988 Apr;15(4):271-4. doi: 10.1111/j.1440-1681.1988.tb01071.x.

The effects of atrial natriuretic polypeptide (ANP) on renal function were examined in renal wrap hypertensive rabbits and sham operated rabbits. 2. ANP (2 micrograms/min) induced hypotension, but did not produce significant diuresis, natriuresis or change in the glomerular filtration rate (GFR) in renal wrap hypertensive rabbits (n = 8). 3. In sham operated normotensive rabbits (n = 4), ANP induced significant diuresis (230%) and increased GFR by about 40%. 4. Thus, ANP was markedly less effective in the impaired kidneys of renal wrapped rabbits than in normal kidneys.

在肾外包高血压兔和假手术兔中研究了心钠素（ANP）对肾功能的影响。2. 心钠素（2微克/分钟）可引起肾外包高血压兔（n = 8）血压降低，但未产生显著的利尿、利钠作用，肾小球滤过率（GFR）也无变化。3. 在假手术的正常血压兔（n = 4）中，心钠素引起显著利尿（230%），肾小球滤过率增加约40%。4. 因此，心钠素在肾外包兔受损肾脏中的作用明显低于正常肾脏。

Takata M, Denton K M, Woods R L, Anderson W P

Emily E. E. Stewart Renal Laboratory, Baker Medical Research Institute, Prahran, Victoria, Australia.

Clin Exp Pharmacol Physiol. 1988 Apr;15(4):271-4. doi: 10.1111/j.1440-1681.1988.tb01071.x.

The effects of atrial natriuretic polypeptide (ANP) on renal function were examined in renal wrap hypertensive rabbits and sham operated rabbits. 2. ANP (2 micrograms/min) induced hypotension, but did not produce significant diuresis, natriuresis or change in the glomerular filtration rate (GFR) in renal wrap hypertensive rabbits (n = 8). 3. In sham operated normotensive rabbits (n = 4), ANP induced significant diuresis (230%) and increased GFR by about 40%. 4. Thus, ANP was markedly less effective in the impaired kidneys of renal wrapped rabbits than in normal kidneys.

在肾外包高血压兔和假手术兔中研究了心钠素（ANP）对肾功能的影响。2. 心钠素（2微克/分钟）可引起肾外包高血压兔（n = 8）血压降低，但未产生显著的利尿、利钠作用，肾小球滤过率（GFR）也无变化。3. 在假手术的正常血压兔（n = 4）中，心钠素引起显著利尿（230%），肾小球滤过率增加约40%。4. 因此，心钠素在肾外包兔受损肾脏中的作用明显低于正常肾脏。