不可思议的纺锤体缩小现象。

The Incredible Shrinking Spindle.

机构信息

Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA 94720-3200, USA.

出版信息

Dev Cell. 2018 May 21;45(4):421-423. doi: 10.1016/j.devcel.2018.05.007.

DOI:10.1016/j.devcel.2018.05.007

Abstract

As cell size decreases during the reductive divisions of early development, intracellular structures must shrink to fit. In this issue of Developmental Cell, Lacroix et al. (2018) identify a conserved mechanism of spindle scaling in nematode and sea urchin embryos whereby spindle microtubule polymerization rates decrease as development proceeds.

摘要

随着早期发育中还原分裂过程中细胞体积的减小，细胞内结构必须缩小以适应。在本期《发育细胞》中，Lacroix 等人（2018 年）发现了一种在线虫和海胆胚胎中保守的纺锤体缩放机制，即随着发育的进行，纺锤体微管聚合速率降低。