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青少年特发性脊柱侧凸术后附加进展的自然史:哪些是进展性附加进展的危险因素?

Natural History of Postoperative Adding-On in Adolescent Idiopathic Scoliosis: What Are the Risk Factors for Progressive Adding-On?

机构信息

Department of Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.

出版信息

Biomed Res Int. 2018 Mar 29;2018:3247010. doi: 10.1155/2018/3247010. eCollection 2018.

Abstract

PURPOSE

To investigate the natural history of distal adding-on in adolescent idiopathic scoliosis (AIS) and to identify risk factors for its progression.

METHODS

Sixty-one AIS patients with distal adding-on occurrence were included. We further classify distal adding-on into progressive and nonprogressive group according to its natural evolution. The first radiograph indicating initiation of adding-on (primary adding-on) and the last follow-up radiograph were compared in terms of the deviation of the first vertebra below instrumentation from the CSVL and the angulation of the first disc below instrumentation. Compared to primary adding-on, progressive adding-on was defined as a further increase of deviation > 5 mm or a further increase of angulation > 5°. Risk factors associated with the progression of adding-on were analyzed.

RESULTS

Among 61 patients diagnosed with distal adding-on, 24 (39.3%) were progressive and 37 (60.7%) were nonprogressive. Lower Risser grade, open triradiate cartilage, and lowest instrumented vertebra (LIV) proximal to Substantially Stable Vertebra (SSV) were found to be significantly associated with the progressive adding-on. Besides, the distal adding-on was more likely to progress for patients with higher left shoulders than right ones after surgery.

CONCLUSIONS

The risk factors for the progression of adding-on included skeletal immaturity, LIV proximal to SSV, and higher left shoulders after surgery.

摘要

目的

研究青少年特发性脊柱侧凸(AIS)中远端附加的自然史,并确定其进展的危险因素。

方法

纳入 61 例 AIS 患者出现远端附加。根据其自然演变,我们进一步将远端附加分为进展性和非进展性组。比较首次出现附加的第一张 X 光片(原发性附加)和最后一次随访的 X 光片,比较器械以下第一椎体偏离 CSVL 和器械以下第一椎间盘的角度。与原发性附加相比,进展性附加定义为进一步增加的偏离 >5mm 或进一步增加的角度 >5°。分析与附加进展相关的危险因素。

结果

在诊断为远端附加的 61 例患者中,24 例(39.3%)为进展性,37 例(60.7%)为非进展性。较低的 Risser 分级、开放三辐射软骨和最低的器械化椎体(LIV)靠近基本稳定的椎体(SSV)与进展性附加显著相关。此外,术后左肩高于右肩的患者远端附加更有可能进展。

结论

进展性附加的危险因素包括骨骼不成熟、SSV 近端的 LIV 和术后左肩较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec10/5896284/ec8a8bf3d812/BMRI2018-3247010.001.jpg

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