Leibniz-Institut für Katalyse e.V. an der Universität Rostock , Albert-Einstein-Str. 29a , Rostock , 18059 , Germany.
Org Lett. 2018 Jun 1;20(11):3422-3425. doi: 10.1021/acs.orglett.8b01368. Epub 2018 May 23.
An interesting selectivity-controlled palladium-catalyzed oxidative carbonylation procedure for the synthesis of propiolates and chromenones has been developed. Starting from phenols and alkynes, under slightly different conditions, various propiolates and chromenones can be isolated in moderate to good yields. Additionally, this also presents the first example of direct carbonylative annulation of nonpreactivated phenols and terminal alkynes to produce chromenones.
现已开发出一种有趣的、选择性控制的钯催化氧化羰基化方法，用于丙炔酸酯和色烯酮的合成。以苯酚和炔烃为起始原料，在略有不同的条件下，可以中等至良好的收率分离得到各种丙炔酸酯和色烯酮。此外，这也是首例直接羰基化芳环化非预活化苯酚和末端炔烃生成色烯酮的实例。
