Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, 18059, Rostock, Germany.
Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, 310018, P. R. China.
Angew Chem Int Ed Engl. 2016 Nov 2;55(45):14151-14154. doi: 10.1002/anie.201608715. Epub 2016 Oct 12.
A novel procedure on the carbonylative synthesis of chromenones has been developed. With simple phenols and internal alkynes as the substrates, various chromenones were isolated in moderate to good yields with excellent regioselectivity and functional-group tolerance by using iridium as the catalyst and copper as the promotor at atmospheric pressure. Notably, this is the first example on carbonylative annulation of simple phenols and alkynes.
一种关于色酮的羰基合成的新方法已经被开发出来。以简单的苯酚和内部炔烃作为底物，在常压下使用铱作为催化剂和铜作为促进剂，以中等至良好的收率分离出各种色酮，具有优异的区域选择性和官能团耐受性。值得注意的是，这是简单苯酚和炔烃羰基环化的第一个例子。
