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从农场到制药:营养基因组学的公共卫生挑战

From farm to pharma: public health challenges of nutrigenomics.

作者信息

Bhardwaj Minakshi

机构信息

Cardiff University, ESRC Centre for Economic and Social Aspects of Genomics (CESAGen) 6, Museum Place, Cardiff CF10 3BG, UK.

出版信息

Per Med. 2007 Nov;4(4):423-430. doi: 10.2217/17410541.4.4.423.

DOI:10.2217/17410541.4.4.423
PMID:29793271
Abstract

Nutrigenomics is speculated to be the next big dimension of genomic sciences geared toward improving public and personal health through nutritional and dietary interventions. This article traces how public health nutrition has been used as an agenda both in agriculture genomics and now in biomedicine. The centrality and importance of food in health and well-being is well recognized and, with the developments in genomics, it has also been used as a tool for public health-related policies and commercialization. This perspective discusses nutrigenomics from four public health perspectives; novel foods and the public health agenda; the epidemic of lifestyle-related diseases, such as obesity, diabetes and cardiovascular diseases; commercialization; and conceptual issues. Several ethical and governance issues in applying nutrigenomics to public health and the implications for public policy will also be considered.

摘要

营养基因组学被推测为基因组科学的下一个重要领域,旨在通过营养和饮食干预改善公众和个人健康。本文追溯了公共卫生营养如何在农业基因组学以及现在的生物医学中被用作一项议程。食物在健康和幸福中的核心地位和重要性已得到充分认可,随着基因组学的发展,它也被用作与公共卫生相关政策和商业化的工具。这一观点从四个公共卫生视角讨论营养基因组学;新型食品与公共卫生议程;与生活方式相关疾病的流行,如肥胖、糖尿病和心血管疾病;商业化;以及概念问题。还将考虑将营养基因组学应用于公共卫生时的一些伦理和治理问题以及对公共政策的影响。

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From farm to pharma: public health challenges of nutrigenomics.从农场到制药:营养基因组学的公共卫生挑战
Per Med. 2007 Nov;4(4):423-430. doi: 10.2217/17410541.4.4.423.
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Precision Nutrition 4.0: A Big Data and Ethics Foresight Analysis--Convergence of Agrigenomics, Nutrigenomics, Nutriproteomics, and Nutrimetabolomics.精准营养4.0:大数据与伦理前瞻性分析——农业基因组学、营养基因组学、营养蛋白质组学和营养代谢组学的融合
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Integrating anticipated nutrigenomics bioscience applications with ethical aspects.将预期的营养基因组学生物科学应用与伦理方面相结合。
OMICS. 2008 Mar;12(1):1-16. doi: 10.1089/omi.2007.0042.
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Ethical considerations in the implementation of nutrigenetics/nutrigenomics.营养遗传学/营养基因组学实施中的伦理考量
Per Med. 2017 Jan;14(1):75-83. doi: 10.2217/pme-2016-0035. Epub 2016 Nov 30.
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Future perspectives of nutrigenomics foods: benefits vs. risks.营养基因组学食品的未来展望:益处与风险
Indian J Biochem Biophys. 2009 Feb;46(1):31-6.
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Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition.国际营养基因学/营养基因组学学会关于个性化营养的指南与立场:第1部分 - 精准营养领域
J Nutrigenet Nutrigenomics. 2016;9(1):12-27. doi: 10.1159/000445350. Epub 2016 May 12.
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Nutrigenomics, individualism and public health.营养基因组学、个性化医疗与公共卫生
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Nutrigenomics and the stewardship of scientific promises.营养基因组学与科学承诺的管理。
Biotechnol J. 2010 Sep;5(9):909-12. doi: 10.1002/biot.201000069.
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Ethical, legal and social issues in nutrigenomics: the challenges of regulating service delivery and building health professional capacity.营养基因组学中的伦理、法律和社会问题:规范服务提供及培养卫生专业人员能力所面临的挑战
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[Nutrigenomics, obesity and public health].[营养基因组学、肥胖与公共卫生]
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引用本文的文献

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The Advent of Nutrigenomics: A Narrative Review with an Emphasis on Psychological Disorders.营养基因组学的出现:一篇侧重于心理障碍的叙述性综述
Prev Nutr Food Sci. 2022 Jun 30;27(2):150-164. doi: 10.3746/pnf.2022.27.2.150.
2
Personalised food: how personal is it?个性化食品:它有多个性化?
Genes Nutr. 2010 Mar;5(1):51-3. doi: 10.1007/s12263-009-0139-0. Epub 2009 Sep 11.