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手术局部麻醉对可膨胀阴茎假体术后疼痛结局的影响:两种药物的前瞻性比较

Effect of operative local anesthesia on postoperative pain outcomes of inflatable penile prosthesis: prospective comparison of two medications.

作者信息

Xie Donghua, Nicholson Marilin, Azaiza Mohammed, Gheiler Victor, Lopez Isabel, Nehrenz Guy M, Klopukh Boris, Bianco Fernando J, Perito Paul, Gheiler Edward

机构信息

Urological Research Network, Hialeah, FL, 33016, USA.

Nova Southeastern University, Fort Lauderdale, FL, 33314, USA.

出版信息

Int J Impot Res. 2018 Jun;30(3):93-96. doi: 10.1038/s41443-018-0025-7. Epub 2018 May 25.

Abstract

Few studies have examined the roles of dorsal penile nerve block (DPNB) and penile ring block (PRB) in surgery of inflatable penile prosthesis (IPP) placement. We sought to compare the postoperative pain outcomes of two different medications used in DPNB plus PRB. We thus carried out a prospective study of patients with erectile dysfunction who underwent "de novo" IPP placement between January 2013 and June 2013. Patients were divided to one of three groups: 1-DPNB plus PRB with bupivacaine injection; 2-DPNB plus PRB with ropivacaine injection and, 3-Control group without DPNB or PRB injection. Postoperative pain score and pain medication usage were recorded 2 h postoperatively, and every 24 h, for a week. The Visual Analog Scale (VAS) was used as pain scale measurement. A total of 131 patients were included in this study: 40 to bupivacaine, 47 to ropivacaine, and the rest were controls. Two hours postoperatively, mean VAS was significantly different (p < 0.0001) between medicated patients and the control group, however, no significant differences were observed between medication groups. Mean VAS was not significantly different among the groups from post-surgical day 2 thru 7. In conclusion, DPNB plus PRB during IPP provided effective analgesia in the immediate post-operative recovery.

摘要

很少有研究探讨阴茎背神经阻滞(DPNB)和阴茎环阻滞(PRB)在可膨胀阴茎假体(IPP)植入手术中的作用。我们试图比较DPNB加PRB中使用的两种不同药物的术后疼痛结果。因此,我们对2013年1月至2013年6月期间接受“初次”IPP植入的勃起功能障碍患者进行了一项前瞻性研究。患者被分为三组之一:1-DPNB加PRB并注射布比卡因;2-DPNB加PRB并注射罗哌卡因,以及3-未进行DPNB或PRB注射的对照组。术后2小时、术后每24小时记录一周的术后疼痛评分和止痛药物使用情况。使用视觉模拟量表(VAS)作为疼痛量表测量。本研究共纳入131例患者:40例接受布比卡因治疗,47例接受罗哌卡因治疗,其余为对照组。术后2小时,用药患者与对照组之间的平均VAS有显著差异(p<0.0001),然而,用药组之间未观察到显著差异。从术后第2天到第7天,各组之间的平均VAS无显著差异。总之,IPP手术期间的DPNB加PRB在术后即刻恢复中提供了有效的镇痛作用。

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