Passias Peter G, Poorman Gregory W, Delsole Edward, Zhou Peter L, Horn Samantha R, Jalai Cyrus M, Vira Shaleen, Diebo Bassel, Lafage Virginie
NYU Medical Center-Hospital for Joint Diseases, New York, NY, USA.
SUNY Downstate Medical Center, Brooklyn, NY, USA.
Global Spine J. 2018 May;8(3):218-223. doi: 10.1177/2192568217718817. Epub 2017 Oct 24.
Retrospective cohort study.
The purpose of this study was to report incidence of cardiopulmonary complications in elective spine surgery, demographic and surgical predictors, and outcomes. Understanding the risks and predictors of these sentinel events is important for risk evaluation, allocation of hospital resources, and counseling patients.
A retrospective review of the National Surgical Quality Improvement Program (NSQIP) was performed on 60 964 patients undergoing elective spine surgery (any region; laminectomy, arthrodesis, discectomy, or laminoplasty) between 2011 and 2013. Incidence of myocardial infarction, cardiac arrest, unplanned reintubation, on ventilator >48 hours, perioperative pneumonia, and pulmonary embolism was measured. Demographic and surgical predictors of cardiopulmonary complications and associated outcomes (length of stay, discharge disposition, and mortality) were measured using binary logistic regression controlling for confounders.
Incidence rates per 1000 elective spine patients were 2.1 myocardial infarctions, 1.3 cardiac arrests, 4.3 unplanned intubations, 3.5 on ventilator >48 hours, 6.1 perioperative pneumonia, and 3.7 pulmonary embolisms. In analysis of procedure, diagnosis, and approach risk factors, thoracic cavity (odds ratio = 2.47; confidence interval = 1.95-3.12), scoliosis diagnosis, and combined approach (odds ratio = 1.51; confidence interval = 1.15-1.96) independently added the most risk for cardiopulmonary complication. Cardiac arrest had the highest mortality rate (34.57%). Being on ventilator greater than 48 hours resulted in the greatest increase to length of stay (17.58 days).
Expected risk factors seen in the Revised Cardiac Risk Index were applicable in the context of spine surgery. Surgical planning should take into account patients who are at higher risk for cardiopulmonary complications and the implications they have on patient outcome.
回顾性队列研究。
本研究旨在报告择期脊柱手术中心肺并发症的发生率、人口统计学和手术预测因素以及结果。了解这些哨兵事件的风险和预测因素对于风险评估、医院资源分配以及为患者提供咨询非常重要。
对2011年至2013年间接受择期脊柱手术(任何区域;椎板切除术、关节融合术、椎间盘切除术或椎板成形术)的60964例患者进行了国家外科质量改进计划(NSQIP)的回顾性分析。测量心肌梗死、心脏骤停、意外再次插管、机械通气超过48小时、围手术期肺炎和肺栓塞的发生率。使用控制混杂因素的二元逻辑回归测量心肺并发症的人口统计学和手术预测因素以及相关结果(住院时间、出院处置和死亡率)。
每1000例择期脊柱手术患者中,心肌梗死发生率为2.1例,心脏骤停发生率为1.3例,意外插管发生率为4.3例,机械通气超过48小时发生率为3.5例,围手术期肺炎发生率为6.1例,肺栓塞发生率为3.7例。在对手术、诊断和入路风险因素的分析中,胸腔手术(比值比=2.47;置信区间=1.95-3.12)、脊柱侧弯诊断和联合入路(比值比=1.51;置信区间=1.15-1.96)独立增加了心肺并发症的最大风险。心脏骤停的死亡率最高(34.57%)。机械通气超过48小时导致住院时间增加最多(17.58天)。
修订后的心脏风险指数中可见的预期风险因素适用于脊柱手术。手术规划应考虑到心肺并发症风险较高的患者及其对患者预后的影响。