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基于智能手机的远程医疗系统对妊娠期糖尿病女性的医学营养治疗

Medical nutrition treatment of women with gestational diabetes mellitus by a telemedicine system based on smartphones.

作者信息

Yang Ping, Lo Wenpin, He Zong-Lin, Xiao Xiao-Min

机构信息

Department of Obstetrics and Gynecology, 1st Affiliated Hospital of Jinan University, Guangzhou, China.

出版信息

J Obstet Gynaecol Res. 2018 Jul;44(7):1228-1234. doi: 10.1111/jog.13669. Epub 2018 May 23.

Abstract

AIM

To explore whether WeChat platform-based treatment of women with gestational diabetes mellitus (GDM) reduces the risk of perinatal complications and explore factors affecting gestational age at delivery.

METHODS

Pregnant women with GDM (n = 107) and normal glucose tolerance (n =50, group C) according to oral glucose tolerance test (OGTT) results during gestational weeks 24-28 were included. Women with GDM were divided into groups A (n =57) and B (n =50) according to informed consent. According to GDM treatment norms, group B was given routine outpatient treatment and health education guidance. In addition to the interventions in group B, group A was given access to both a smartphone-based telemedicine system and articles providing continuous health education. The PBG level in groups A and B was compared, as were differences in maternal and fetal outcomes. Data were analyzed by t-test, analysis of variance (anova), chi-square test and multiple linear regression, with P < 0.05 considered significant.

RESULTS

Fasting blood glucose (FBG) and 2-h postprandial blood glucose (PBG) were significantly lower and premature delivery was significantly less likely in group A than in group B (all P < 0.05). Compared with group B, caesarean section was more likely in group A (P < 0.05). Pregnancy-induced hypertension had a higher incidence in group B than in group C (P < 0.05). Gestational age at delivery was associated with OGTT2h, premature fetal membrane rupture and self-monitoring of blood glucose.

CONCLUSION

GDM treatment based on the WeChat platform effectively reduces FBG and 2-h PBG and may improve pregnancy outcomes. However, 1-h PBG was not affected by treatment. Obstetricians should consider the OGTT2h value to increase gestational age at delivery.

摘要

目的

探讨基于微信平台对妊娠期糖尿病(GDM)女性的治疗是否能降低围产期并发症风险,并探究影响分娩孕周的因素。

方法

纳入根据孕24 - 28周口服葡萄糖耐量试验(OGTT)结果诊断为GDM的孕妇(n = 107)以及糖耐量正常的孕妇(n = 50,C组)。根据知情同意情况,将GDM孕妇分为A组(n = 57)和B组(n = 50)。按照GDM治疗规范,B组给予常规门诊治疗及健康教育指导。A组除B组的干预措施外,还可使用基于智能手机的远程医疗系统并获取提供持续健康教育的文章。比较A组和B组的餐后血糖(PBG)水平以及母婴结局差异。数据采用t检验、方差分析(anova)、卡方检验和多元线性回归进行分析,P < 0.05认为差异有统计学意义。

结果

A组的空腹血糖(FBG)和餐后2小时血糖(PBG)显著低于B组,且早产发生率显著低于B组(均P < 0.05)。与B组相比,A组剖宫产的可能性更大(P < 0.05)。B组妊娠高血压的发生率高于C组(P < 0.05)。分娩孕周与OGTT2小时值、胎膜早破和血糖自我监测有关。

结论

基于微信平台的GDM治疗可有效降低FBG和餐后2小时PBG,并可能改善妊娠结局。然而,餐后l小时PBG不受治疗影响。产科医生应考虑OGTT2小时值以增加分娩孕周。

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