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注射器与中式杯在负压吸疱移植供皮区创面的应用:一项随机自身对照研究。

Syringes versus Chinese cups in harvesting suction-induced blister graft: a randomized split-body study.

机构信息

Department of Dermatology, STD's and Andrology, Minia University, Minia, Egypt.

Dermatology and Venereology Department, Faculty of Medicine for Girls, Al Azhar University, Cairo, Egypt.

出版信息

Int J Dermatol. 2018 Oct;57(10):1249-1252. doi: 10.1111/ijd.14040. Epub 2018 May 24.

Abstract

BACKGROUND

Suction blister grafting (SBG) is a technique where the pigmented epidermis is harvested from the donor site by induction of a blister using different suction methods as syringes, Chinese cups, suction device, etc. However, pain, time consumption, incomplete blister formation, and failure of blister development are the main limitations.

OBJECTIVE

To compare between cups and syringes of similar diameter in inducing suction blisters.

PATIENTS AND METHODS

In 30 patients with stable nonsegmental vitiligo, 2-cm-diameter (20 ml) syringe was applied on the anterolateral aspect of one thigh and a 2-cm-diameter cup on the corresponding site of the other thigh where right and left sides were chosen randomly. Patients were observed untill complete blister development or for a maximum of 3 hours. Suction blister induction time (SBIT) and the blister diameter were recorded for each patient. Pain during the process of induction was evaluated.

RESULTS

Incomplete blister development was noted in 9 out of 30 (30%) with 2 cm syringes and 6 out of 30 (20%) with the similar diameter cups with no significant difference (P = 0.49). No significant difference was found between SBIT induced by the 2 cm syringes and the similar size cups (101.17 ± 68.14 minutes, 98 ± 56.84 minutes, respectively) (P = 0.85). Meanwhile, blister diameter induced by either syringe or cup was not significantly different (P = 0.37). Anesthesia was for short duration with xylocaine, and pain was intolerable in both sides in the first seven patients. A combination of xylocaine and bupivacaine was used with prolonged loss of pain in 17 of the remaining 23 patients and tolerable pain in six patients similarly in both sides.

CONCLUSION

According to present results, the differences in SIBT, diameter of blisters, and number of complete blister formation induced by either syringes or cups of similar size were not significant. Therefore, whatever the available and feasible technique for the surgeon will be the ideal choice. A combination of xylocaine and bupivacaine is recommended to overcome the accompanying pain of the procedure.

摘要

背景

抽吸疱皮移植术(SBG)是一种通过使用不同的抽吸方法(如注射器、中国杯、抽吸装置等)在供体部位诱导水疱来获取色素表皮的技术。然而,疼痛、时间消耗、不完全水疱形成和水疱发育失败是主要的限制因素。

目的

比较直径相似的杯和注射器在诱导抽吸疱皮中的效果。

患者和方法

在 30 例稳定的非节段性白癜风患者中,在一侧大腿的前外侧应用 2cm 直径(20ml)的注射器,在对侧大腿的相应部位应用 2cm 直径的杯,左右两侧随机选择。患者被观察至完全水疱形成或最长 3 小时。记录每位患者的抽吸疱皮诱导时间(SBIT)和水疱直径。评估诱导过程中的疼痛。

结果

在 30 例患者中,有 9 例(30%)用 2cm 注射器和 6 例(20%)用类似直径的杯出现不完全水疱形成,无显著差异(P=0.49)。用 2cm 注射器和类似大小的杯诱导的 SBIT 之间无显著差异(101.17±68.14 分钟,98±56.84 分钟)(P=0.85)。同时,用注射器或杯诱导的水疱直径无显著差异(P=0.37)。用利多卡因进行短暂麻醉,前 7 例患者两侧疼痛难以忍受。在其余 23 例患者中的 17 例中,使用利多卡因和布比卡因的组合,疼痛持续时间延长,在 6 例患者中,两侧的疼痛同样可以忍受。

结论

根据目前的结果,用直径相似的注射器或杯诱导的 SBIT、水疱直径和完全水疱形成的数量差异无统计学意义。因此,无论外科医生使用哪种可行的技术,都将是理想的选择。建议使用利多卡因和布比卡因的组合来克服手术伴随的疼痛。

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