Anbar Tag S, El-Fakahany Hasan M, El-Khayyat Mohammed A, Abdel-Rahman Amal T, Saad Enas K
Department of Dermatology, STD's and Andrology, Minia University, Minia, Egypt.
Department of Dermatology, STD's and Andrology, Matay Central Hospital, Minia, Egypt.
J Cosmet Dermatol. 2020 Jul;19(7):1723-1729. doi: 10.1111/jocd.13222. Epub 2019 Nov 20.
Suction blister grafting (SBG) technique has been used for long to treat various skin conditions. Different suction methods have been used such as syringes, Chinese cups, and suction device. There are some limitations of its use as time consumption, failure of induction or incomplete blister formation and pain.
The aim of this work was to evaluate the outcome of using two different suction techniques, namely the syringes and the Chinese cups in induction of suction blisters. The effect of the device diameter and preheating of the donor area on the suction blister induction time (SBIT) was studied. The effect of saline injection in the blister formation and its completion was also evaluated.
The study was a left-right comparative study that included 50 patients with stable nonsegmental vitiligo. They were classified into four groups: Group 1 included 15 patients where different diameters of syringes (1.3, 1.7, and 2 cm) were compared against each other, group 2 included 15 patients where different diameters of cups (2, 3.5, and 5 cm) were compared against each other, group 3 included 20 patients subdivided into two groups; 10 patients each, where the effect of preheating the skin on blister induction was tested with use of cups (3a) and syringes (3b). Lastly, group 4 included randomly chosen 40 incomplete or multilocular blisters where the effect of saline injection on blister completion and coalescence of multilobulation was examined. SBIT was calculated in all patients.
The use of the small diameter syringes or cups gave shorter SBIT; however, the difference, which was significant between all sizes of cups, was significant between the 1.3- and 2-cm-diameter syringes only. Preheating of the donor area shorten SBIT significantly. No complications were reported at the donor site except for transient postinflammatory hyperpigmentation in all patients.
The small diameter syringes or cups and preheating of the donor area shorten the SBIT, while intra-blister saline injection increased the blister size and turns the multilocular blisters to unilocular ones.
吸疱移植（SBG）技术长期以来一直用于治疗各种皮肤疾病。已使用不同的抽吸方法，如注射器、火罐和抽吸装置。其使用存在一些局限性，如耗时、诱导失败或水疱形成不完全以及疼痛。
本研究的目的是评估使用两种不同抽吸技术（即注射器和火罐）诱导吸疱的效果。研究了装置直径和供皮区预热对吸疱诱导时间（SBIT）的影响。还评估了水疱内注射生理盐水对水疱形成及其完整性的影响。
本研究为左右对照研究，纳入50例稳定型非节段性白癜风患者。他们被分为四组：第1组包括15例患者，比较不同直径（1.3、1.7和2 cm）的注射器；第2组包括15例患者，比较不同直径（2、3.5和5 cm）的火罐；第3组包括20例患者，分为两组，每组10例，分别测试使用火罐（3a）和注射器（3b）时皮肤预热对水疱诱导的影响。最后，第4组随机选取40个不完全或多房性水疱，检查水疱内注射生理盐水对水疱完整性和多房融合的影响。计算所有患者的SBIT。
使用小直径注射器或火罐的SBIT较短；然而，所有尺寸火罐之间的差异有统计学意义，仅1.3 cm和2 cm直径的注射器之间的差异有统计学意义。供皮区预热显著缩短SBIT。除所有患者均出现短暂的炎症后色素沉着外，供皮区未报告并发症。
小直径注射器或火罐以及供皮区预热可缩短SBIT，而水疱内注射生理盐水可增加水疱大小并使多房性水疱变为单房性水疱。
