Ding Li, Wang Jun, Yang Haoxia, Yu Jun
Department of Rehabilitation Medicine, Wuxi City Ninth People's Hospital, Wuxi 214000, Jiangsu Province, China.
Zhongguo Zhen Jiu. 2018 May 12;38(5):4633-7. doi: 10.13703/j.0255-2930.2018.05.003.
To compare the clinical efficacy differences between "governor vessel method of acupuncture" combined with estazolam and estazolam alone for insomnia.
Seventy patients of insomnia were randomly divided into an observation group and a control group, 35 cases in each one. The patients in the control group were treated with oral administration of estazolam, 2 mg each time; the estazolam was taken 30 min before sleeping. The patients in the observation group were treated with "governor vessel method of acupuncture" combined with estazolam; the positive reaction points along governor vessel and Baihui (GV 20) were selected as the main points. The acupuncture was given for 30 min per treatment, once every two days. Both groups were treated for four weeks. Pittsburgh sleep quality index (PSQI) and polysomnography (PSG) were observed before and after treatment. Clinical efficacy was assessed between the two groups and adverse reactions were recorded.
The total effective rate was 94.3% (33/35) in the observation group, which had no significant difference with 82.9% (29/35) in the control group (>0.05). The cured and markedly effective rate was 71.4% (25/35) in the observation group, which was superior to 42.9% (15/35) in the control group (<0.05). Each item score and total score of PSQI were decreased obviously after treatment in the observation group (all <0.05), while the score of sleep latency, sleep duration and sleep efficiency as well as total score of PSQI were decreased obviously after treatment in the control group (all <0.05). The scores of sleep duration, sleep disturbance and day dysfunction due to sleepiness as well as total score of PSQI in the observation group were lower than that in the control group (all <0.05). After treatment, the PSG-related parameters of total sleeping duration, sleeping latency, sleeping arousal and sleeping efficiency were improved significantly in the observation group (all <0.05); the total sleeping duration, sleeping arousal and sleeping efficiency were also improved in the control group (all <0.05). The total sleeping duration, sleeping latency, sleeping arousal and sleeping efficiency in the observation group were superior to those in the control group (all <0.05). 4 adverse reactions in the observation group and 3 adverse reactions in the control group were observed.
"Governor vessel method of acupuncture" combined with estazolam could significantly improve insomnia, which are superior to estazolam alone.
比较“督脉针刺法”联合艾司唑仑与单纯使用艾司唑仑治疗失眠的临床疗效差异。
将70例失眠患者随机分为观察组和对照组，每组35例。对照组患者口服艾司唑仑治疗，每次2mg，于睡前30分钟服用。观察组患者采用“督脉针刺法”联合艾司唑仑治疗，选取督脉及百会穴（GV20）沿线的阳性反应点为主穴。每次治疗针刺30分钟，每两天治疗1次。两组均治疗4周。观察治疗前后的匹兹堡睡眠质量指数（PSQI）和多导睡眠图（PSG）。评估两组的临床疗效并记录不良反应。
观察组总有效率为94.3%（33/35），与对照组的82.9%（29/35）比较，差异无统计学意义（>0.05）。观察组痊愈及显效率为71.4%（25/35），优于对照组的42.9%（15/35）（<0.05）。观察组治疗后PSQI各项目评分及总分均明显降低（均<0.05），对照组治疗后睡眠潜伏期、睡眠时间、睡眠效率评分及PSQI总分均明显降低（均<0.05）。观察组的睡眠时间、睡眠障碍及日间困倦所致功能障碍评分及PSQI总分均低于对照组（均<0.05）。治疗后，观察组PSG相关的总睡眠时间、睡眠潜伏期、睡眠觉醒及睡眠效率参数均明显改善（均<0.05）；对照组的总睡眠时间、睡眠觉醒及睡眠效率也有所改善（均<0.05）。观察组的总睡眠时间、睡眠潜伏期、睡眠觉醒及睡眠效率均优于对照组（均<0.05）。观察组观察到4例不良反应，对照组观察到3例不良反应。
“督脉针刺法”联合艾司唑仑能显著改善失眠，效果优于单纯使用艾司唑仑。
