Li Oujing, Wang Fan
Department of TCM, Asian Sports Village Community Health Service Center, Beijing 100101, China.
Department of Acupuncture and Moxibustion, Beijing Tibetan Hospital of China Tibetology Research Center, Beijing 100029.
Zhongguo Zhen Jiu. 2018 May 12;38(5):4693-72. doi: 10.13703/j.0255-2930.2018.05.005.
To compare the clinical efficacy differences between acupuncture at back- points of five , Geshu (BL 17), Shenmen (HT 7) and regular medication for the treatment of menopausal insomnia.
A total of 128 female patients of menopausal insomnia were randomly divided into an observation group and a control group, 64 cases in each one. Four patients in the observation group and 2 patients in the control group dropped out during the treatment. The patients in the observation group were treated with acupuncture at Feishu (BL 13), Xinshu (BL 15), Pishu (BL 20), Ganshu (BL 18), Shenshu (BL 23), Geshu (BL 17) and Shenmen (HT 7), once a day, and there was an interval of 2 days between every 5 days of treatment. The patients in the control group were treated with oral administration of alprazolam (0.4 mg or 0.8 mg) before sleep. Three-week treatment was taken as one course, and totally three courses were given in the two groups. Pittsburgh sleep quality index (PSQI), levels of estradiol (E), follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were observed before treatment and 30 days after treatment; the efficacy was evaluated 30 days after treatment.
Each item score and total score of PSQI 30 days after treatment were lower than those before treatment in the two groups (all <0.05), the scores in the observation group were lower than those in the control group (all <0.05). The levels of E 30 days after treatment were higher than those before treatment in the two groups (both <0.05), but the level of FSH and LH 30 days after treatment were lower than those before treatment in the two groups; the level in the observation group was superior to that in the control group (all <0.05). The total effective rate was 98.3% (59/60) in the observation group, which was better than 95.2% (59/62) in the control group (<0.05).
Acupuncture at Feishu (BL 13), Xinshu (BL 15), Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23), Geshu (BL 17), and Shenmen (HT 7) has better efficacy for menopausal insomnia than alprazolam.
比较针刺背部五腧穴、膈俞(BL 17)、神门(HT 7)与常规药物治疗更年期失眠的临床疗效差异。
将128例更年期失眠女性患者随机分为观察组和对照组,每组64例。治疗期间观察组有4例患者、对照组有2例患者脱落。观察组采用针刺肺俞(BL 13)、心俞(BL 15)、脾俞(BL 20)、肝俞(BL 18)、肾俞(BL 23)、膈俞(BL 17)、神门(HT 7),每日1次,每5次治疗间隔2天。对照组于睡前口服阿普唑仑(0.4 mg或0.8 mg)。以3周治疗为1个疗程,两组均共进行3个疗程。观察治疗前及治疗30天后的匹兹堡睡眠质量指数(PSQI)、雌二醇(E)、卵泡刺激素(FSH)及黄体生成素(LH)水平;治疗30天后评价疗效。
两组治疗30天后PSQI各条目评分及总分均低于治疗前(均P<0.05),观察组评分低于对照组(均P<0.05)。两组治疗30天后E水平高于治疗前(均P<0.05),但治疗30天后FSH及LH水平低于治疗前;观察组水平优于对照组(均P<0.05)。观察组总有效率为98.3%(59/60),优于对照组的95.2%(59/62)(P<0.05)。
针刺肺俞(BL 13)、心俞(BL 15)﹑肝俞(BL 18)、脾俞(BL 20)、肾俞(BL 23)、膈俞(BL 17)、神门(HT 7)治疗更年期失眠的疗效优于阿普唑仑。