Wang Z, Tian Y, Jiang X J
Department of Otorhinolaryngology, First Affiliated Hospital,China Medical University,Shenyang.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Dec;30(23):1846-1849. doi: 10.13201/j.issn.1001-1781.2016.23.003.
To analyze the relationship of tinnitus and early stage damage of cochlear, to explore the clinical applied value of distortion product otoacoustic emission(DPOAE) and auditory brainstem response(ABR) in the bilateral tinnitus patients with normal hearing capability. There are 30 cases(60 ears) in the tinnitus group with bilateral tinnitus patients with normal hearing capability, and there are 30 cases(60 ears) in the control group without tinnitus of normal hearing capability. The two groups both test the DPOAE and ABR,and compare the results of the DPOAE and ABR. The passing rate of DPOAE in all frequencies was 100% in the control group,42.67% in the tinnitus group. Significant differences existed between the two groups(<0.05).The DPOAE could be checked out at all frequencies under 2 kHz except 0.75 kHz in the tinnitus group, and the passing rates of DPOAE were significantly lower than those in control group(<0.05).There were 3 cases could not be checked out at 0.75 kHz frequency, but there were no significant difference(>0.05).The DPOAE amplitudes at frequencies of 3 to 8 kHz in tinnitus ears were significantly lower than those in nontinnitus ears(the P value were 0.011,0.013,0.008,0.027 ).Wave Ⅰ,Ⅲ and Ⅴcould be detected in all ears tested at 80 dB nHL. The latencies of WaveⅠin tinnitus group were obviously prolonged.The latencies of Wave Ⅲ and Ⅴ in tinnitus group were also prolonged, but there was no significant difference(>0.05).The interval between waves Ⅰand Ⅲ,waves Ⅲ and Ⅴand wavesⅠand Ⅴ showed no difference. The maybe cochlear early injury in fractional bilateral tinnitus patients with normal hearing capability, DPOAE and ABR can act as an objective method for diagnosing peripheral tinnitus.
分析耳鸣与耳蜗早期损害的关系,探讨畸变产物耳声发射(DPOAE)及听性脑干反应(ABR)在听力正常的双侧耳鸣患者中的临床应用价值。耳鸣组为30例(60耳)听力正常的双侧耳鸣患者,对照组为30例(60耳)听力正常无耳鸣者。两组均检测DPOAE及ABR,并比较其结果。对照组各频率DPOAE通过率均为100%,耳鸣组为42.67%,两组间差异有统计学意义(<0.05)。耳鸣组除0.75kHz外,2kHz以下各频率均可引出DPOAE,其通过率均显著低于对照组(<0.05)。0.75kHz频率有3例未引出DPOAE,但差异无统计学意义(>0.05)。耳鸣耳3~8kHz频率DPOAE幅值显著低于非耳鸣耳(P值分别为0.011、0.013、0.008、0.027)。所有测试耳在80dB nHL时均可引出波Ⅰ、Ⅲ、Ⅴ。耳鸣组波Ⅰ潜伏期明显延长,波Ⅲ、Ⅴ潜伏期也延长,但差异无统计学意义(>0.05)。波Ⅰ与Ⅲ、波Ⅲ与Ⅴ、波Ⅰ与Ⅴ之间的间期无差异。听力正常的双侧耳鸣患者可能存在耳蜗早期损伤,DPOAE和ABR可作为诊断外周性耳鸣的客观方法。