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[单侧急性耳鸣患者耳蜗的电生理研究]

[Electrophysiological study of the cochlea in patients with unilateral acute tinnitus].

作者信息

Wu Wenli, Ding Lei, Gao Mingyuan, Huang Chuanghui, Wang Dongmei, Jiang Hui, Wei Ran

机构信息

Department of Otolaryngology,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing,100078,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 May;36(5):357-361. doi: 10.13201/j.issn.2096-7993.2022.05.007.

Abstract

To analyze the objective test results of the pure-tone audiogram (PTA), extended high-frequency audiometry (EHFA), distortion product otoacoustic emission (DPOAE), auditory brainstem response(ABR), and electrocochleogram (ECochG) in patients with unilateral acute tinnitus, summarize their characteristics and explore their clinical application value in hidden hearing loss. PTA, DPOAE, ABR, and ECochG tests were performed in 33 patients with unilateral acute tinnitus as the chief complaint. The detection rate and response amplitude of each DPOAE frequency, incubation period, and interval of ABR waves and -SP/AP in ECochG were analyzed. ①The thresholds of PTA at 0.25-8 kHz in both ears were in the normal range (>0.05), and the thresholds of PTA at 9-16 kHz in affected ears were higher than those in healthy ears (<0.001); ②There was statistical significance in the detection rate and response amplitude of DPOAE at 3, 4, 6, 8 kHz between ears (<0.05); ③The incubation period of ABR Ⅰ wave in affected ears was (1.55±0.17) ms, that in the healthy ear was (1.50±0.14) ms, among them, the incubation period of ABR Ⅰ wave in the affected ear was longer than that in the healthy ear, and the difference was statistically significant (<0.05); ④In ECochG, there was no significant difference in -SP amplitude between ears (>0.05), but there was a significant difference in AP amplitude and -SP/AP amplitude between ears (<0.05). EHFA, DPOAE, ABR, and ECochG have clinical significance in evaluating cochlear function in tinnitus patients.

摘要

分析单侧急性耳鸣患者的纯音听力图(PTA)、扩展高频听力测定(EHFA)、畸变产物耳声发射(DPOAE)、听性脑干反应(ABR)及耳蜗电图(ECochG)的客观测试结果,总结其特点并探讨其在隐匿性听力损失中的临床应用价值。对33例以单侧急性耳鸣为主诉的患者进行PTA、DPOAE、ABR及ECochG测试。分析各DPOAE频率的检出率及反应幅值、ABR波的潜伏期及波间期以及ECochG中的-SP/AP。①双耳0.25 - 8kHz的PTA阈值均在正常范围内(>0.05),患耳9 - 16kHz的PTA阈值高于健耳(<0.001);②双耳间3、4、6、8kHz的DPOAE检出率及反应幅值有统计学意义(<0.05);③患耳ABRⅠ波潜伏期为(1.55±0.17)ms,健耳为(1.50±0.14)ms,其中患耳ABRⅠ波潜伏期长于健耳,差异有统计学意义(<0.05);④在ECochG中,双耳间-SP幅值无显著差异(>0.05),但AP幅值及-SP/AP幅值双耳间有显著差异(<0.05)。EHFA、DPOAE、ABR及ECochG在评估耳鸣患者的耳蜗功能方面具有临床意义。

相似文献

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[Electrophysiological study of the cochlea in patients with unilateral acute tinnitus].[单侧急性耳鸣患者耳蜗的电生理研究]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 May;36(5):357-361. doi: 10.13201/j.issn.2096-7993.2022.05.007.
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[Application of objective audiological tests in bilateral tinnitus patients with normal hearing capability].客观听力测试在听力正常的双侧耳鸣患者中的应用
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Dec;30(23):1846-1849. doi: 10.13201/j.issn.1001-1781.2016.23.003.

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[Research progress in auditory center plasticity and tinnitus mechanism].[听觉中枢可塑性与耳鸣机制的研究进展]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Nov;35(11):1038-1041. doi: 10.13201/j.issn.2096-7993.2021.11.017.
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Sensory Neuron Diversity in the Inner Ear Is Shaped by Activity.内耳感觉神经元的多样性由活动塑造。
Cell. 2018 Aug 23;174(5):1229-1246.e17. doi: 10.1016/j.cell.2018.07.007. Epub 2018 Aug 2.
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Toward a Differential Diagnosis of Hidden Hearing Loss in Humans.迈向人类隐匿性听力损失的鉴别诊断
PLoS One. 2016 Sep 12;11(9):e0162726. doi: 10.1371/journal.pone.0162726. eCollection 2016.

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