Jin L, Yu S Q, Zhang X, Ge Q, Zhang X L, Wang Y, Qin M L
Department of Otorhinolaryngology Head and Neck Surgery, Tongji Hospital, Tongji Medical University, Shanghai, 200065, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Apr;32(7):493-496. doi: 10.13201/j.issn.1001-1781.2018.07.004.
To investigate the effectiveness and safety of nasal lavage with hydrogen-rich saline in the treatment of moderate to severe allergic rhinitis.Twenty patients with moderate to severe persistent allergic rhinitis were treated with normal saline and hydrogen-rich saline lavage the nasal cavity. The study was randomized doubl-blind self-control study. The symptoms and signs score, treatment index and total effective rate were evaluated before and after treatment, and the nasal conjunctivitis related quality of life questionnaire (BQLQ) was used to evaluate the life quality of patients.There were significant differences of the symptoms, signs scores, the treatment index, the total efficiency and BQLQ between the two kinds of lavage fluid used for patients before and after treatment(<0.05). No significant adverse reactions occurred during follow-up.Hydrogen-enriched saline is safe and effective for allergic rhinitis.
探讨富氢盐水鼻腔灌洗治疗中重度变应性鼻炎的有效性及安全性。20例中重度持续性变应性鼻炎患者分别用生理盐水和富氢盐水进行鼻腔灌洗。本研究为随机双盲自身对照研究。治疗前后评估症状体征评分、治疗指数及总有效率，采用鼻结膜炎相关生活质量问卷（BQLQ）评估患者生活质量。两种灌洗液治疗前后患者的症状、体征评分、治疗指数、总有效率及BQLQ比较，差异均有统计学意义（<0.05）。随访期间未发生明显不良反应。富氢盐水治疗变应性鼻炎安全有效。
