Zhang T Y, Shang X L, Xie Y X, Lin Y T, Zhang Q J, Li D, Xin Y C
Hebei North University,Zhangjiakou,075000,China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Apr;32(7):537-540. doi: 10.13201/j.issn.1001-1781.2018.07.015.
To study the effects of postauricular injection of methylprednisolone on medium-high frequency sudden hearing loss.The data of 45 patients with invalid treatment who were diagnosed as medium-high frequency sudden hearing loss were retrospectively studied. They were divided into postauricular injection group and non-postauricular injection group. The treatment efficiency and hearing improvement at each frequency were compared between the two groups.The improvements of hearing threshold in the non-postauricular injection group were(6.30±5.00)dB HL,(3.80±5.52)dB HL,(5.35±5.50)dB HL,(15.60±11.84)dB HL,(19.60±13.46)dB HL,(15.40±12.90)dB HL at 250, 500, 1000, 2000, 4000 and 8000Hz, respectively. The hearing improvements of the postauricular injection group were (5.35±6.22)dB HL,(2.50±3.00)dB HL,(4.65±6.60)dB HL,(23.75±10.75)dB HL,(25.75±11.73)dB HL,(30.50±14.50)dB HL at 250, 500,1000,2000,4000 and 8000Hz, respectively. There were significant differences between the two groups in hearing improvements at 2000-8000Hz. The treatment effective rates were 44% and 80% for the non-postauricular injection group and postauricular injection group respectively, which showed a significant difference(χ²=8.385<0.05).Postauricular injection of methylprednisolone as a remedy treatment is safe and effective for sudden hearing loss in middle and high frequency.
研究耳后注射甲泼尼龙对中高频突发性听力损失的影响。回顾性研究45例诊断为中高频突发性听力损失且治疗无效患者的数据。将其分为耳后注射组和非耳后注射组。比较两组的治疗有效率及各频率听力改善情况。非耳后注射组在250、500、1000、2000、4000和8000Hz频率时听力阈值改善分别为(6.30±5.00)dB HL、(3.80±5.52)dB HL、(5.35±5.50)dB HL、(15.60±11.84)dB HL、(19.60±13.46)dB HL、(15.40±12.90)dB HL。耳后注射组在250、500、1000、2000、4000和8000Hz频率时听力改善分别为(5.35±6.22)dB HL、(2.50±3.00)dB HL、(4.65±6.60)dB HL、(23.75±10.75)dB HL、(25.75±11.73)dB HL、(30.50±14.50)dB HL。两组在2000 - 8000Hz频率的听力改善有显著差异。非耳后注射组和耳后注射组的治疗有效率分别为44%和80%，差异有统计学意义(χ²=8.385<0.05)。耳后注射甲泼尼龙作为补救治疗对中高频突发性听力损失安全有效。
