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耳后局部注射联合口服激素治疗平坦型突发性聋的临床疗效分析

[Clinical curative effect analysis of postauricular topical injection combining with oral hormone in the treatment of the flat type of sudden hearing loss].

作者信息

Gao Y, Wang C L, Zheng Y

机构信息

Department of Otorhinolaryngology, the Affiliated Second Hospital, Xinjiang Medical University, Urumqi, 830038, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Nov 5;31(21):1639-1641. doi: 10.13201/j.issn.1001-1781.2017.21.004.

DOI:10.13201/j.issn.1001-1781.2017.21.004
PMID:29798117
Abstract

To analyze the clinical curative effect of postauricular topical injection combining with oral hormone in the treatment of the flat type of sudden hearing loss.Data of 128 patients with the Sudden hearing lossfrom year 2015 till now were collected, and randomly divided into two groups: postauricular topical injection group (methylprednisolone sodium succinatefor injection 40 mg+linocaine 2.5 ml, retroauricular groove topical injection, qod, combining with taking methylprednisolone tablets 24 mg in the morning for 3 days) and non-postauricular injection group (take methylprednisolone tablets 24 mg in the morning for 3 days). Use SPSS 17.0 software to analyze the hearing curativeeffect of these two groups statistically.The cure rate of postauricular injection group: 23.4%(15 cases), effect appear: 14.1%(9 cases), valid: 37.5%(24 cases), invalid:25.0%(16 cases), total effective rate:75%(48/64).The difference compare of these two group has a statistically significant (< 0.05).②The cure rate of the flat type patients with the postauricular injection treatment among the total 64 cases is 23.4%, which is higher than the patients without the postauricular injection treatment.The difference compare of these two group has a statistically significant (< 0.05).③The incrementsof the postauricular injection group in 250-8 000 Hz, which is divided into7different frequencies, from low to high, are (26.48±6.23)dBHL, (23.24±4.21)dBHL, (21.89±7.34)dBHL, (26.07±7.01)dBHL, (25.75±5.14)dBHL.The mean value compare of frequency 250-500 Hz and 250-4 000 Hz of these two group has a statistically significant (< 0.05).The curative effect of postauricular topical injection combining with oral hormone in the treatment of the flat type of sudden hearing loss is better than only oral hormone.

摘要

分析耳后局部注射联合口服激素治疗平坦型突发性聋的临床疗效。收集2015年至今128例突发性聋患者的资料,随机分为两组:耳后局部注射组(注射用甲泼尼龙琥珀酸钠40mg+利多卡因2.5ml,耳后沟局部注射,隔日1次,同时晨起口服甲泼尼龙片24mg,共3天)和非耳后注射组(晨起口服甲泼尼龙片24mg,共3天)。采用SPSS 17.0软件对两组的听力疗效进行统计学分析。耳后注射组治愈率:23.4%(15例),显效:14.1%(9例),有效:37.5%(24例),无效:25.0%(16例),总有效率:75%(48/64)。两组差异比较有统计学意义(<0.05)。②64例中采用耳后注射治疗的平坦型患者治愈率为23.4%,高于未采用耳后注射治疗的患者。两组差异比较有统计学意义(<0.05)。③耳后注射组在250 - 8000Hz共7个不同频率下的听力提升值,由低到高分别为(26.48±6.23)dBHL、(23.24±4.21)dBHL、(21.89±7.34)dBHL、(26.07±7.01)dBHL、(25.75±5.14)dBHL。两组在250 - 500Hz及250 - 4000Hz频率的均值比较有统计学意义(<0.05)。耳后局部注射联合口服激素治疗平坦型突发性聋的疗效优于单纯口服激素。

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