Min M K, Zhu M H, Zheng H L
Department of Otorhinolaryngology Head and Neck Surgery, Changhai Hospital, Second Military Medical University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Nov 20;31(22):1770-1774. doi: 10.13201/j.issn.1001-1781.2017.22.018.
Head and neck squamous cell carcinoma, HNSCC, has high morbidity and mortality. Even in America, more than 1/2 to 2/3 patients have been diagnosed at advanced stage. So, it's urgent to find ways to diagnose HNSCC earlier and foresee the curative effect. With the achievement of Next-Generation Sequencing, researchers are trying to develop early diagnostic technology from a new perspective, such as personal genomics, proteomics, metabolomics and other related personal information. Here we reviewed the recent research in early diagnosis of HNSCC.
头颈部鳞状细胞癌（HNSCC）具有较高的发病率和死亡率。即使在美国，超过二分之一至三分之二的患者在确诊时已处于晚期。因此，迫切需要找到更早诊断HNSCC并预测疗效的方法。随着新一代测序技术的发展，研究人员正试图从新的角度开发早期诊断技术，如个人基因组学、蛋白质组学、代谢组学及其他相关个人信息。在此，我们综述了HNSCC早期诊断的最新研究。
