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生长因子缓释微球在脂肪移植中的研究进展

[Research progress of growth factor sustained-release microspheres in fat transplantation].

作者信息

Chen Zhuojie, Cheng Qian, Yu Xiaofang, He Yucang, Li Liqun

机构信息

Department of Plastic Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou Zhejiang, 325000, P.R.China.

Department of Plastic Surgery, Huangyan Hospital Affiliated to Wenzhou Medical University, Taizhou Zhejiang, 318020, P.R.China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2017 Nov 15;31(11):1402-1406. doi: 10.7507/1002-1892.201703125.

Abstract

OBJECTIVE

To review the research progress of growth factor sustained-release microspheres in fat transplantation.

METHODS

The recently published 1iterature at home and abroad related the growth factor sustained-release microspheres in fat transplantation was reviewed and analyzed.

RESULTS

The sustained-release microsphere carrier materials include natural polymer materials and synthetic polymer materials.The sustained-release complexes of different microsphere materials with different growth factors can promote the vascularization of transplanted fat in a timely manner, improve the survival rate of grafts, and reduce the incidence of complications such as liquefaction, calcification, and necrosis.

CONCLUSION

The growth factor sustained-release microspheres have the characteristics of persistence and controllability, which is a research hotspot in the field of fat transplantation and has broad application prospects.

摘要

目的

综述生长因子缓释微球在脂肪移植中的研究进展。

方法

回顾并分析国内外近期发表的有关生长因子缓释微球在脂肪移植方面的文献。

结果

缓释微球载体材料包括天然高分子材料和合成高分子材料。不同微球材料与不同生长因子形成的缓释复合物可及时促进移植脂肪的血管化,提高移植物的存活率,降低液化、钙化、坏死等并发症的发生率。

结论

生长因子缓释微球具有持续性和可控性等特点,是脂肪移植领域的研究热点,具有广阔的应用前景。

相似文献

1
[Research progress of growth factor sustained-release microspheres in fat transplantation].生长因子缓释微球在脂肪移植中的研究进展
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2017 Nov 15;31(11):1402-1406. doi: 10.7507/1002-1892.201703125.
2
[Research progress on controlled release of various growth factors in bone regeneration].[骨再生中多种生长因子控释的研究进展]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2019 Jun 15;33(6):750-755. doi: 10.7507/1002-1892.201901116.

本文引用的文献

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Polylactic acid (PLA) controlled delivery carriers for biomedical applications.用于生物医学应用的聚乳酸(PLA)控释载体。
Adv Drug Deliv Rev. 2016 Dec 15;107:163-175. doi: 10.1016/j.addr.2016.06.018. Epub 2016 Jul 15.
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Extracellular Matrix Revisited: Roles in Tissue Engineering.细胞外基质再探讨:在组织工程中的作用
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J Control Release. 2015 May 28;206:161-76. doi: 10.1016/j.jconrel.2015.03.020. Epub 2015 Mar 20.

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