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非肌层浸润性膀胱癌患者生活质量和性功能随访评估:前瞻性描述性研究的初步结果

Assessment of the quality of life and sexual functions of patients followed-up for non-muscle invasive bladder cancer: preliminary results of the prospective-descriptive study.

作者信息

Bolat Deniz, Çelik Serdar, Aydın Mehmet Erhan, Aydoğdu Özgü, Günlüsoy Bülent, Değirmenci Tansu, Dinçel Çetin

机构信息

Clinic of Urology, Bozyaka Training and Research Hospital, İzmir, Turkey.

出版信息

Turk J Urol. 2018 Sep;44(5):393-398. doi: 10.5152/tud.2018.30040. Epub 2017 Sep 12.

Abstract

OBJECTIVE

The aim of this study is to evaluate sexual functions and quality life of patients who are followed-up for non-muscle invasive bladder cancer (NMIBC).

MATERIAL AND METHODS

Between March 2015-June 2016, 50 patients underwent cystoscopy for NMIBC. At the end of the 1 year follow-up patients were assessed for sexual functions using 5-item version of the International Sexual Function Index (IIEF-5) for male and the Female Sexual Function Index(FSFI) for female; for quality of life (QoL) by the European Organisation for Research and Treatment of Cancer-Non-Muscle Invasiv Bladder Cancer Quality of Life Questionnaire (EORTC QLQ-NMIBC24) and for emotional status by Beck depression inventory.

RESULTS

There were 44 male and 6 female patients with the mean age of 57.6±11.5 years. Twenty patients received intravesical treatment after transurethral resection of bladder tumour. The mean Beck (10.7±9.5) IIEF-5 (15.6±5.9), FSFI (19.2±10.9), and the EORTC-QLQ NMBIC 24 (38.2±7.7) scores of the patients were determined as indicated. Among the patients, 42 (84%) of them were not feeling bad about their bladder tumors and 37 (74%) were not worrying about their daily lives. Moreover, 12 (24%) patients were not interested with sexuality, while 27 (54%) of them did not feel comfortable about sexual sincerity. Interestingly, 27 patients receiving intravesical treatment were concerned that the treatment they received for prevention of recurrence and progression of bladder tumor infect their partners during sexual intercourse.

CONCLUSION

NMIBC affects patients' sexual functions and QoL negatively. Therefore during the follow-up of these patients, it is important to inform these patients accurately about their treatments to be applied and predicted complications in the follow up period.

摘要

目的

本研究旨在评估非肌层浸润性膀胱癌(NMIBC)患者的性功能和生活质量。

材料与方法

2015年3月至2016年6月期间,50例患者因NMIBC接受了膀胱镜检查。在1年随访结束时,使用国际性功能指数5项版本(IIEF-5)评估男性患者的性功能,使用女性性功能指数(FSFI)评估女性患者的性功能;通过欧洲癌症研究与治疗组织-非肌层浸润性膀胱癌生活质量问卷(EORTC QLQ-NMIBC24)评估生活质量,通过贝克抑郁量表评估情绪状态。

结果

共有44例男性和6例女性患者,平均年龄为57.6±11.5岁。20例患者在经尿道膀胱肿瘤切除术后接受了膀胱内治疗。患者的平均贝克(10.7±9.5)、IIEF-5(15.6±5.9)、FSFI(19.2±10.9)和EORTC-QLQ NMBIC 24(38.2±7.7)评分如所示。在患者中,42例(84%)对膀胱肿瘤感觉良好,37例(74%)不担心日常生活。此外,12例(24%)患者对性不感兴趣,而其中27例(54%)对性真诚度感到不舒服。有趣的是,27例接受膀胱内治疗的患者担心他们为预防膀胱肿瘤复发和进展而接受的治疗在性交过程中会感染伴侣。

结论

NMIBC对患者的性功能和生活质量有负面影响。因此,在对这些患者进行随访期间,准确告知他们拟应用的治疗方法以及随访期间可能出现的并发症非常重要。

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