砂仁的化学成分、药理作用、临床应用、专利及产品研究进展。
Phytochemicals, pharmacology, clinical application, patents, and products of Amomi fructus.
机构信息
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao.
State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu City, Sichuan Province, China.
出版信息
Food Chem Toxicol. 2018 Sep;119:31-36. doi: 10.1016/j.fct.2018.05.051. Epub 2018 May 24.
Amomi fructus (A. fructus) (Sharen) is a well-known traditional Chinese medicine widely used to treat gastrointestinal diseases. It has high medical and economic values, which have been confirmed both in vitro and in vivo studies. This review highlights the phytochemicals, pharmacology, clinical application, patents, and products of A. fructus. More than 100 phytochemicals have been isolated and identified from A. fructus, mainly including volatile oils, saponins, flavonoids, organic acids, inorganic ingredients, and polysaccharides. The main pharmacology of gastrointestinal protection, anti-inflammatory activity, analgesic activity, antidiarrheal activity, antibacterial activity, anti-microbial activity and hypoglycemic activity have been confirmed. The main clinical applications include functional digestion disorder, gastritis, helicobacter pylori infection in children and treatment of mastitis. There are 23 patents and 405 different drug products of A. fructus.
砂仁（A. fructus）（Sharen）是一种广受欢迎的中药，常用于治疗胃肠道疾病。其具有较高的医学和经济价值，在体外和体内研究中均得到证实。本综述重点介绍了砂仁的植物化学物质、药理学、临床应用、专利和产品。从砂仁中已分离鉴定出 100 多种植物化学物质，主要包括挥发油、皂苷、黄酮类、有机酸、无机成分和多糖。其胃肠道保护、抗炎活性、镇痛活性、抗腹泻活性、抗菌活性、抗微生物活性和降血糖活性已得到证实。主要的临床应用包括功能性消化障碍、胃炎、儿童幽门螺杆菌感染和乳腺炎的治疗。砂仁有 23 项专利和 405 种不同的药物产品。
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