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基于细菌纤维素的抗菌复合敷料的研究进展

[Advances in the research of antibacterial composite dressings based on bacterial cellulose].

作者信息

Luo Z H, Zhang J P

机构信息

State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burn Research, the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038, China.

出版信息

Zhonghua Shao Shang Za Zhi. 2018 May 20;34(5):314-317. doi: 10.3760/cma.j.issn.1009-2587.2018.05.014.

DOI:10.3760/cma.j.issn.1009-2587.2018.05.014
PMID:29804430
Abstract

Bacterial cellulose (BC) is a promising material for wound dressing due to its predominant water binding capacity, mechanical property, biodegradability, and histocompatibility. Whereas BC itself exhibits no antimicrobial activity. To gain antimicrobial activity, several kinds of antibacterial agents have been introduced into BC. However, all of the antibacterial composite dressings are still in the stage of experimental research. In this paper, the types, antibacterial mechanism, and shortcomings of antibacterial composite dressings based on BC are summarized, in order to make prospects of the research trends of antibacterial composite dressings based on BC in future.

摘要

细菌纤维素(BC)因其卓越的保水能力、机械性能、生物可降解性和组织相容性,是一种很有前景的伤口敷料材料。然而,BC本身不具有抗菌活性。为了获得抗菌活性,已将几种抗菌剂引入BC中。然而,所有抗菌复合敷料仍处于实验研究阶段。本文总结了基于BC的抗菌复合敷料的类型、抗菌机制和缺点,以期展望未来基于BC的抗菌复合敷料的研究趋势。

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