Brandt Andreas Hjelm, Hansen Kristoffer Lindskov, Ewertsen Caroline, Holbek Simon, Olesen Jacob Bjerring, Moshavegh Ramin, Thomsen Carsten, Jensen Jørgen Arendt, Nielsen Michael Bachmann
Department of Radiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Department of Radiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Ultrasound Med Biol. 2018 Aug;44(8):1751-1761. doi: 10.1016/j.ultrasmedbio.2018.05.002. Epub 2018 May 24.
Magnetic resonance phase contrast angiography (MRA) is the gold standard for blood flow evaluation. Spectral Doppler ultrasound (SDU) is the first clinical choice, although the method is angle dependent. Vector flow imaging (VFI) is an angle-independent ultrasound method. The aim of the study was to compare VFI- and SDU-estimated peak systolic velocities (PSV) of the common carotid artery (CCA) with PSV obtained by MRA. Furthermore, intra- and inter-observer agreement was determined. MRA estimates were significantly different from SDU estimates (left CCA: p < 0.001, right CCA: p < 0.001), but not from VFI estimates (left CCA: p = 0.28, right CCA: p = 0.18). VFI measured lower PSV in both CCAs compared with SDU (p < 0.001) with improved precision (VFI: left: 24%, right: 18%; SDU: left 38%, right: 23%). Intra- and inter-observer agreement was almost perfect for VFI and SDU (inter-observer correlation coefficient: VFI 0.88, SDU 0.91; intra-observer correlation coefficient: VFI 0.96, SDU 0.97). VFI is more accurate than SDU in evaluating PSV compared with MRA.
磁共振相位对比血管造影（MRA）是血流评估的金标准。频谱多普勒超声（SDU）是临床首选方法，尽管该方法依赖角度。向量血流成像（VFI）是一种不依赖角度的超声方法。本研究的目的是比较VFI和SDU估计的颈总动脉（CCA）收缩期峰值速度（PSV）与MRA获得的PSV。此外，还确定了观察者内和观察者间的一致性。MRA估计值与SDU估计值有显著差异（左CCA：p < 0.001，右CCA：p < 0.001），但与VFI估计值无显著差异（左CCA：p = 0.28，右CCA：p = 0.18）。与SDU相比，VFI测量的两侧CCA的PSV均较低（p < 0.001），且精度更高（VFI：左侧24%，右侧18%；SDU：左侧38%，右侧23%）。VFI和SDU的观察者内和观察者间一致性几乎完美（观察者间相关系数：VFI为0.88，SDU为0.91；观察者内相关系数：VFI为0.96，SDU为0.97）。与MRA相比，VFI在评估PSV方面比SDU更准确。
