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[用于评估肥胖患者心肺适能的摄氧动力学]

[Oxygen uptake kinetics to assess cardiorespiratory fitness in obese patients].

作者信息

Miranda Claudia, Ibacache Paulina, Opazo Edgardo, Rojas Juan, Cano Marcelo

机构信息

Escuela de Kinesiología, Facultad de Ciencias de la Rehabilitación, Universidad Andres Bello, Santiago, Chile.

Departamento de Kinesiología, Universidad de Chile, Chile.

出版信息

Rev Med Chil. 2018 Jan;146(1):15-21. doi: 10.4067/s0034-98872018000100015.

Abstract

BACKGROUND

The evaluation of cardiorespiratory fitness (RCC) using maximal or peak oxygen consumption (VO2), requires a high level of effort in obese patients. We propose a method to evaluate RCC using constant and moderate loads, called VO2 kinetics (tau).

AIM

To determine the relationship between tau and peak VO2 in patients with obesity.

MATERIAL AND METHODS

Forty patients (87% females) aged 37 ± 12 years and with a body mass index (BMI) of 34.6 ± 4.0 kg/m2, were divided into two groups according to the applied workload (0.5 and 0.8 Watts/kg body mass) using a cycle ergometer and Cortex Metalyzer 3b equipment. The protocol was started with 6 minutes at constant load and then increments of 20-25 Watts every two min were made until determination of the peak VO2.

RESULTS

The tau value was 51.8 ± 17.6 s, the absolute peak VO2 was 2.0 ± 0.7 L/min and the relative peak VO2 was 26.6 ± 30.0 ml/kg/min. There was a significant difference of tau medians between the group that used 0.5 and 0.8 Watts/kg (p = 0.002) and a significant inverse correlation between the absolute peak VO2 and the tau value for a load of 0.5 Watts/kg (rho = -0.415, p = 0.0327).

CONCLUSIONS

The higher tau value, the lower the peak VO2 of an obese patient. It is suggested to apply loads of 0.5 Watts/kg for a VO2 kinetics test in obese patients or in subjects who do not wish to carry out higher physiological demands with a non-invasive and low risk procedure.

摘要

背景

使用最大或峰值耗氧量(VO₂)评估心肺适能(RCC),对肥胖患者而言需要付出高强度努力。我们提出一种使用恒定和中等负荷来评估RCC的方法,称为VO₂动力学(tau)。

目的

确定肥胖患者中tau与峰值VO₂之间的关系。

材料与方法

40名年龄为37±12岁、体重指数(BMI)为34.6±4.0kg/m²的患者(87%为女性),使用自行车测力计和Cortex Metalyzer 3b设备,根据所施加的工作量(0.5和0.8瓦/千克体重)分为两组。方案开始时先进行6分钟的恒定负荷,然后每隔两分钟增加20 - 25瓦,直至确定峰值VO₂。

结果

tau值为51.8±17.6秒,绝对峰值VO₂为2.0±0.7升/分钟,相对峰值VO₂为26.6±30.0毫升/千克/分钟。使用0.5和0.8瓦/千克的两组之间tau中位数存在显著差异(p = 0.002),对于0.5瓦/千克的负荷,绝对峰值VO₂与tau值之间存在显著的负相关(rho = -0.415,p = 0.0327)。

结论

肥胖患者的tau值越高,其峰值VO₂越低。建议在肥胖患者或不希望通过无创且低风险程序进行更高生理需求测试的受试者中,应用0.5瓦/千克的负荷进行VO₂动力学测试。

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