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资源匮乏环境下的偶发发现结果返还:是救援还是……

Returning Incidental Findings in Low-Resource Settings: A Case of Rescue?

出版信息

Hastings Cent Rep. 2018 May;48(3):28-30. doi: 10.1002/hast.852.

DOI:10.1002/hast.852
PMID:29806889
Abstract

In a carefully argued article, Haley K. Sullivan and Benjamin E. Berkman address the important question of whether investigators have a duty to report incidental findings to research participants in low-resource settings. They suggest that the duty to rescue offers the most plausible justification for the duty to return incidental findings, and they explore the implications of this duty for the context of research in low-resource settings. While I think they make valuable headway on an important problem, in this commentary, I identify a significant difference between the paradigmatic rescue case and the return of incidental findings in low-resource settings. This difference, I suggest, implies that their framework may be too narrow in scope. If investigators (and their sponsors) really wish to fulfill their duty to rescue, they must consider factors that are left out of Sullivan and Berkman's framework.

摘要

在一篇精心论证的文章中,Haley K. Sullivan 和 Benjamin E. Berkman 探讨了一个重要问题,即研究人员是否有责任向资源匮乏环境中的研究参与者报告偶发发现。他们认为,救援义务为回报偶发发现的义务提供了最合理的理由,并探讨了这一义务对资源匮乏环境下研究背景的影响。虽然我认为他们在一个重要问题上取得了有价值的进展,但在这篇评论中,我指出了典范救援案例和资源匮乏环境下回报偶发发现之间的一个显著差异。我认为,这种差异意味着他们的框架可能过于狭隘。如果研究人员(及其资助者)真的希望履行救援义务,他们就必须考虑到 Sullivan 和 Berkman 框架中遗漏的因素。

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1
Returning Incidental Findings in Low-Resource Settings: A Case of Rescue?资源匮乏环境下的偶发发现结果返还:是救援还是……
Hastings Cent Rep. 2018 May;48(3):28-30. doi: 10.1002/hast.852.
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Incidental Findings in Low-Resource Settings.低资源环境下的偶然发现。
Hastings Cent Rep. 2018 May;48(3):20-28. doi: 10.1002/hast.851.
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Rescue via Genetic Findings.通过基因发现进行救援。
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The duty to rescue in genomic research.基因组研究中的救助义务。
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Association of Researcher Characteristics with Views on Return of Incidental Findings from Genomic Research.研究者特征与对基因组研究中偶然发现结果反馈看法的关联
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Legal implications of an ethical duty to search for genetic incidental findings.寻找基因偶然发现的伦理义务的法律影响
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'Ethical responsibility' or 'a whole can of worms': differences in opinion on incidental finding review and disclosure in neuroimaging research from focus group discussions with participants, parents, IRB members, investigators, physicians and community members.“道德责任”还是“一团麻烦事”:通过与参与者、家长、机构审查委员会成员、研究人员、医生及社区成员进行焦点小组讨论,了解在神经影像研究中对偶然发现的审查与披露方面的意见分歧
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