母乳喂养与产妇年龄相关性白内障。

Breastfeeding and Maternal Age-related Cataract.

机构信息

Center for International Health Research, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA; Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.

Department of Health Convergence, Ewha Womans University, Seoul, South Korea.

出版信息

Am J Ophthalmol. 2018 Aug;192:124-130. doi: 10.1016/j.ajo.2018.05.017. Epub 2018 May 26.

DOI:10.1016/j.ajo.2018.05.017

PMID:29806992

Abstract

PURPOSE

No studies addressed the influence of breastfeeding on cataract formation. The objective of this study was to address the relationship between breastfeeding and maternal age-related cataract.

DESIGN

A nationwide cross-sectional study.

METHODS

This study analyzed data for 3821 parous women aged 50 years or above in the Korea National Health and Nutrition Examination Survey 2010-2012. Participants were aggregated into quartiles according to the number of breastfed children and duration of breastfeeding. Logistic regression analysis was used to examine the relationships between less or short duration of breastfeeding and increased risks of cataract.

RESULTS

A total of 2197 women (57.5%) were classified as having age-related cataract. Women who breastfed 4-12 children (odds ratio [OR] = 0.56; 95% confidence interval [CI] = 0.35-0.89) had significantly lower risks for cortical cataract, compared to those who breastfed no or 1 child (P for trend across quartiles = .010). Women who breastfed for 36-60 months (OR = 0.61, 95% CI = 0.42-0.90) or 61-324 months (OR = 0.53, 95% CI = 0.33-0.83) had lower risks for cortical cataract compared to those who breastfed 16 months or less (P for trend across tertiles = .003). The population-attributable fractions of cortical cataract induced by number of children breastfed less than 3 and duration of breastfeeding less than 36 months were 9.4% (95% CI = 1.3%-17.6%) and 10.7% (95% CI = 3.0%-18.4%), respectively.

CONCLUSIONS

Breastfeeding more children and long-term breastfeeding were associated with lower risk of cortical cataract formation in parous women.

摘要

目的

没有研究探讨母乳喂养对白内障形成的影响。本研究旨在探讨母乳喂养与女性年龄相关性白内障之间的关系。

设计

一项全国性的横断面研究。

方法

本研究分析了 2010-2012 年韩国国家健康和营养调查中 3821 名 50 岁及以上的经产妇女的数据。参与者根据母乳喂养儿童的数量和母乳喂养的持续时间被分为四组。使用逻辑回归分析来检验母乳喂养时间较短或较短与白内障风险增加之间的关系。

结果

共有 2197 名妇女（57.5%）被归类为患有年龄相关性白内障。与母乳喂养 1 个或无子女的妇女相比，母乳喂养 4-12 个子女的妇女（皮质性白内障的优势比[OR]为 0.56；95%置信区间[CI]为 0.35-0.89），皮质性白内障的风险显著降低（各四分位数间趋势检验的 P 值=0.010）。母乳喂养 36-60 个月（OR=0.61，95%CI=0.42-0.90）或 61-324 个月（OR=0.53，95%CI=0.33-0.83）的妇女皮质性白内障的风险较低，与母乳喂养 16 个月或以下的妇女相比（各三分位间趋势检验的 P 值=0.003）。由母乳喂养儿童数少于 3 个月和母乳喂养持续时间少于 36 个月引起的皮质性白内障的人群归因分数分别为 9.4%（95%CI=1.3%-17.6%）和 10.7%（95%CI=3.0%-18.4%）。