Mustafa Osama M, Daoud Yassine J
Cornea, Cataract, and Refractive Surgery Division, Wilmer Eye Institute, The Johns Hopkins University, Baltimore, MD, USA.
Ophthalmic Epidemiol. 2021 Jun;28(3):244-249. doi: 10.1080/09286586.2020.1817505. Epub 2020 Sep 4.
An estimated 38 million and 50 million individuals will have cataract in the U.S. alone by 2030 and 2050, respectively. Breastfeeding is known to improve a number of health outcomes in both breastfed children and breastfeeding mothers. However, little is known about the relationship between breastfeeding and cataract, the leading cause of blindness worldwide, in breastfeeding mothers. This study was conducted to investigate the relationship between breastfeeding and maternal cataract extraction history in a nationally representative sample of the U.S. population.
A 10-year multistage, probability-sampling survey data was used to identify parous women aged ≥50 years who provided breastfeeding history and cataract extraction history (n = 4897). Breastfeeding history was considered positive if a participant reported breastfeeding at least one child for ≥1 month. The main outcome was cataract extraction history. Estimates are presented in odds ratios (OR) and 95% confidence intervals (95%CI).
Approximately half of the studied women breastfed at least one child ≥1 month, and about 18% reported cataract extraction history. Participants with a positive breastfeeding history were less likely to have a positive cataract extraction history in both age-adjusted (OR = 0.814, 95%CI = 0.670-0.989) and multivariable logistic regression (OR = 0.794, 95%CI = 0.639-0.988). Higher number of breastfed children was also associated with a lower risk of cataract extraction history (OR = 0.934, 95%CI = 0.883-0.988).
The findings suggest that breastfeeding may be associated with a decrease in the likelihood of age-related cataract extraction in parous women from the U.S. population.
预计到2030年和2050年，仅在美国就将分别有3800万和5000万人患有白内障。众所周知，母乳喂养对母乳喂养的儿童和母亲的多种健康状况都有改善作用。然而，对于母乳喂养与全球失明的主要原因——白内障之间的关系，在母乳喂养的母亲中却知之甚少。本研究旨在调查美国具有全国代表性的样本中母乳喂养与母亲白内障摘除史之间的关系。
使用一项为期10年的多阶段概率抽样调查数据，以识别年龄≥50岁且提供了母乳喂养史和白内障摘除史的经产妇（n = 4897）。如果参与者报告至少母乳喂养一个孩子≥1个月，则母乳喂养史被视为阳性。主要结果是白内障摘除史。估计值以比值比（OR）和95%置信区间（95%CI）表示。
大约一半的研究女性至少母乳喂养一个孩子≥1个月，约18%报告有白内障摘除史。在年龄调整（OR = 0.814，95%CI = 0.670 - 0.989）和多变量逻辑回归（OR = 0.794，95%CI = 0.639 - 0.988）中，有阳性母乳喂养史的参与者有阳性白内障摘除史的可能性较小。母乳喂养孩子数量较多也与白内障摘除史风险较低相关（OR = 0.934，95%CI = 0.883 - 0.988）。
研究结果表明，母乳喂养可能与美国经产妇年龄相关性白内障摘除可能性的降低有关。
