Mitchell A, Guyatt G, Singer J, Irvine E J, Goodacre R, Tompkins C, Williams N, Wagner F
School of Nursing, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
J Clin Gastroenterol. 1988 Jun;10(3):306-10. doi: 10.1097/00004836-198806000-00014.
To investigate the effect of inflammatory bowel disease (IBD) on the quality of life, we interviewed 43 patients with ulcerative colitis (UC) and 54 with Crohn's disease. Patients identified frequent and important problems in five areas. Primary bowel symptoms, systemic symptoms, and altered emotional function were common; functional and social impairment were less frequent. Systemic symptoms such as fatigue were more prevalent in patients with Crohn's disease. Apart from primary bowel complaints, patients seldom volunteered other facets of quality of life impairment; this was particularly true for impairment of emotional function. We conclude that despite troublesome intestinal and systemic symptoms, most patients with IBD avoid major disruption in work and personal lives. Physicians must inquire specifically about emotional problems relating to IBD; in particular, fear of surgery is important to address. Psychosocial interventions should be targeted to those patients with problems in this area.
为研究炎症性肠病（IBD）对生活质量的影响，我们对43例溃疡性结肠炎（UC）患者和54例克罗恩病患者进行了访谈。患者指出了五个方面常见且重要的问题。主要肠道症状、全身症状以及情绪功能改变较为常见；功能和社会功能受损则相对较少见。疲劳等全身症状在克罗恩病患者中更为普遍。除了主要的肠道问题外，患者很少主动提及生活质量受损的其他方面；情绪功能受损尤其如此。我们得出结论，尽管存在令人烦恼的肠道和全身症状，但大多数IBD患者在工作和个人生活中并未受到重大干扰。医生必须特别询问与IBD相关的情绪问题；特别是，解决对手术的恐惧很重要。心理社会干预应针对该领域存在问题的患者。
