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婴儿手术时间超过 60 分钟的脊髓麻醉:脊髓麻醉项目实施头 2 年的经验。

Spinal anesthesia for surgery longer than 60 min in infants: experience from the first 2 years of a spinal anesthesia program.

机构信息

Department of Anesthesiology, Pain Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH, 43205, USA.

Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.

出版信息

J Anesth. 2018 Aug;32(4):637-640. doi: 10.1007/s00540-018-2517-5. Epub 2018 May 28.

Abstract

PURPOSE

Spinal anesthesia (SA) is being increasingly used in infants to avoid the potential negative neurocognitive effects of general anesthesia (GA). However, SA has been reported to provide a relatively short duration of surgical anesthesia.

METHODS

We retrospectively reviewed SA cases for surgical procedures lasting more than 60 min in children up to 3 years old. All patients received bupivacaine 0.5% (1 mg/kg up to 7 mg) with clonidine 1 µg/kg ± epinephrine. The primary outcome was success of SA without subsequent conversion to GA.

RESULTS

Thirty-five patients met inclusion criteria (all males, age 7 ± 5 months, weight 8 ± 2 kg). Procedures included male genital, groin and multiple site surgeries. Average surgical duration was 71 ± 12 min (range 60-111 min). SA was successful in 31 of 35 patients (89%; 95% confidence interval 78, 99%). The cause of failure was rarely due to the duration of surgery (1 of 4 patients). Six patients with successful SA required sedation with dexmedetomidine ± fentanyl. Differences in procedure duration and patient characteristics were not statistically significant between successful and failed SA.

CONCLUSIONS

SA is a highly successful technique and may offer an alternative to GA in children undergoing appropriate surgery expected to last as long as 60-100 min.

摘要

目的

椎管内麻醉(SA)在婴儿中越来越多地被用于避免全身麻醉(GA)可能产生的神经认知负面影响。然而,已有报道称 SA 提供的手术麻醉持续时间相对较短。

方法

我们回顾性地审查了在 3 岁以下儿童中接受手术时间超过 60 分钟的 SA 病例。所有患者均接受 0.5%布比卡因(1mg/kg 至 7mg)加 1μg/kg 氯胺酮±肾上腺素。主要结局是 SA 成功而无需随后转为 GA。

结果

35 名患者符合纳入标准(均为男性,年龄 7±5 个月,体重 8±2kg)。手术包括男性生殖器、腹股沟和多处手术。平均手术时间为 71±12 分钟(范围 60-111 分钟)。35 例患者中有 31 例(89%;95%置信区间 78,99%)SA 成功。失败的原因很少是手术时间(4 例中有 1 例)。6 例成功实施 SA 的患者需要接受右美托咪定±芬太尼镇静。SA 成功与失败的患者在手术持续时间和患者特征方面没有统计学差异。

结论

SA 是一种非常成功的技术,可作为在预计持续 60-100 分钟左右的适当手术中 GA 的替代方法。

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