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小儿泌尿外科手术的脊髓麻醉:降低全身麻醉的理论神经毒性作用。

Spinal anesthesia for pediatric urological surgery: Reducing the theoretic neurotoxic effects of general anesthesia.

作者信息

Whitaker Emmett E, Wiemann Brianne Z, DaJusta Daniel G, Alpert Seth A, Ching Christina B, McLeod Daryl J, Tobias Joseph D, Jayanthi Venkata R

机构信息

Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, OH 43210, USA; Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, OH 43205, USA.

The Ohio State University College of Medicine, Columbus, OH 43210, USA.

出版信息

J Pediatr Urol. 2017 Aug;13(4):396-400. doi: 10.1016/j.jpurol.2017.06.006. Epub 2017 Jul 14.

Abstract

BACKGROUND

Spinal anesthesia (SA) is an effective technique that has been used in children for years. With growing concern with regard to the risks of general anesthesia (GA), we developed a SA program to provide an alternative option. We present our initial experience with this program.

OBJECTIVE

To implement a SA program at a large tertiary care pediatric center and assess the safety and efficacy of the technique as an alternative to GA for urologic surgery.

STUDY DESIGN/METHODS: We prospectively collected data on all children undergoing SA at our institution. We recorded demographics, procedure, time required for placement of the SA, length of surgery, success of lumbar puncture, success of attaining adequate surgical anesthesia, need for supplemental systemic sedation, conversion to GA, and perioperative complications.

RESULTS

SA was attempted in 105 consecutive children (104 boys, 1 girl) with a mean age of 7.4 ± 4.3 months (range 19 days-24 months) and mean weight of 8.3 ± 1.7 kg (range 3.5-13.7). Placement of the SA was successful in 93/105 children (89%). Inability to achieve lumbar puncture (cerebrospinal fluid was not obtained) meant that SA was abandoned in seven (7%) patients and GA was administered. In five patients in whom SA was successful and surgery was begun, 5/93 (5%) required conversion to GA: two because of evisceration of intestine through large hernia defects related to coughing and abdominal irritation, two because of lack of motor blockade despite an adequate sensory block, and one because of an inability to place an intravenous catheter in the lower extremities (required per SA protocol). If necessary, an intravenous catheter can be placed in the upper extremity, but this must be weighed against the fact that the block has already been placed and is of limited duration. Overall, SA was successful (SA was placed and surgery was completed without conversion to GA) in 88/105 children (84%). No additional sedation and no systemic anesthetic agents were required in 75/88 children (85%). The average time required to place the SA was 3.8 ± 2.7 min (range 1-12). The average time for the surgical procedure was 38.3 ± 23.1 min (range 10-122). No patient required conversion to GA because of recession of block. There were no surgical complications.

DISCUSSION/CONCLUSIONS: SA is a safe and efficacious technique for routine pediatric urological procedures. SA should be considered for cases such as neonatal torsion or patients with significant cardiac or pulmonary comorbidities when the risks of GA are often weighed against the risks of non-intervention.

摘要

背景

脊髓麻醉(SA)是一种多年来一直在儿童中使用的有效技术。随着对全身麻醉(GA)风险的日益关注,我们制定了一项SA计划以提供替代选择。我们介绍了该计划的初步经验。

目的

在一家大型三级儿科护理中心实施SA计划,并评估该技术作为GA替代方案用于泌尿外科手术的安全性和有效性。

研究设计/方法:我们前瞻性地收集了在本机构接受SA的所有儿童的数据。我们记录了人口统计学信息、手术过程、SA置管所需时间、手术时长、腰椎穿刺成功率、获得足够手术麻醉的成功率、补充全身镇静的需求、转为GA的情况以及围手术期并发症。

结果

连续105名儿童(104名男孩,1名女孩)尝试进行SA,平均年龄为7.4±4.3个月(范围19天至24个月),平均体重为8.3±1.7千克(范围3.5至13.7千克)。105名儿童中有93名(89%)SA置管成功。无法进行腰椎穿刺(未获取到脑脊液)意味着7名(7%)患者放弃SA并接受GA。在5名SA成功且手术开始的患者中,93名中有5名(5%)需要转为GA:2名是因为通过与咳嗽和腹部刺激相关的大疝缺损导致肠脱出,2名是因为尽管感觉阻滞充分但缺乏运动阻滞,1名是因为无法在下肢放置静脉导管(根据SA方案要求)。如有必要,可在上肢放置静脉导管,但这必须与已经进行了阻滞且持续时间有限这一事实相权衡。总体而言,105名儿童中有88名(84%)SA成功(SA置管成功且手术完成,未转为GA)。88名儿童中有75名(85%)无需额外镇静和全身麻醉剂。SA置管的平均所需时间为3.8±2.7分钟(范围1至12分钟)。手术的平均时长为38.3±23.1分钟(范围10至122分钟)。没有患者因阻滞消退而需要转为GA。没有手术并发症。

讨论/结论:SA是用于常规儿科泌尿外科手术的一种安全有效的技术。对于新生儿扭转或患有严重心脏或肺部合并症等情况,当GA风险常与不干预风险相权衡时,应考虑使用SA。

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