Camargo Carlos Henrique Ferreira, Bronzini Augusto, Tolentino Eduardo de Souza, Medyk Camila, Schultz-Pereira Gustavo Leopold
Serviço de Neurologia, Hospital Universitário Regional dos Campos Gerais, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brasil.
Arq Neuropsiquiatr. 2018 Mar;76(3):145-149. doi: 10.1590/0004-282x20180003.
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery was created to assess cognitive impairment in Alzheimer's disease (AD) but it is widely-used for various dementias. The aim of this study was to analyze the efficacy of using the CERAD battery in the assessment of patients with Parkinson's disease. Forty-nine patients with Parkinson's disease were divided into two groups (one with dementia and one without) using the Movement Disorder Society criteria for Parkinson's disease dementia. Cognitive deficits were assessed with the Clinical Dementia Rating Scale as the gold standard, and the CERAD. The ROC curve for the CERAD battery had an area under the curve = 0.989 (95% CI = 0.967 - 1, p<0.0001). Among the CERAD subtests, verbal fluency had the worst accuracy, and word list learning had the best accuracy. Despite the limits of this study, the CERAD battery can be efficient for assessment of cognitive deficits in Parkinson's disease patients.
阿尔茨海默病注册协会（CERAD）神经心理成套测验旨在评估阿尔茨海默病（AD）中的认知障碍，但它被广泛用于各种痴呆症。本研究的目的是分析使用CERAD成套测验评估帕金森病患者的有效性。根据运动障碍协会的帕金森病痴呆标准，将49例帕金森病患者分为两组（一组有痴呆，一组无痴呆）。以临床痴呆评定量表作为金标准，采用CERAD评估认知缺陷。CERAD成套测验的ROC曲线下面积=0.989（95%CI=0.967-1，p<0.0001）。在CERAD子测验中，语言流畅性的准确性最差，单词列表学习的准确性最好。尽管本研究存在局限性，但CERAD成套测验对于评估帕金森病患者的认知缺陷可能是有效的。
