Department of Chemistry, Iowa State University, Ames, IA, USA.
J Sep Sci. 2018 Aug;41(15):3081-3088. doi: 10.1002/jssc.201800415. Epub 2018 Jun 15.
An ionic-liquid-based in situ dispersive liquid-liquid microextraction method coupled to headspace gas chromatography and mass spectrometry was developed for the rapid analysis of ultraviolet filters. The chemical structures of five ionic liquids were specifically designed to incorporate various functional groups for the favorable extraction of the target analytes. Extraction parameters including ionic liquid mass, molar ratio of ionic liquid to metathesis reagent, vortex time, ionic strength, pH, and total sample volume were studied and optimized. The effect of the headspace temperature and volume during the headspace sampling step was also evaluated to increase the sensitivity of the method. The optimized procedure is fast as it only required ∼7-10 min per extraction and allowed for multiple extractions to be performed simultaneously. In addition, the method exhibited high precision, good linearity, and low limits of detection for six ultraviolet filters in aqueous samples. The developed method was applied to both pool and lake water samples attaining acceptable relative recovery values.
建立了一种基于离子液体的原位分散液液微萃取方法，结合顶空气相色谱和质谱法，用于快速分析紫外线过滤器。五种离子液体的化学结构经过专门设计，包含各种功能基团，有利于目标分析物的提取。研究并优化了萃取参数，包括离子液体的质量、离子液体与相转移试剂的摩尔比、涡旋时间、离子强度、pH 值和总样品体积。还评估了顶空采样步骤中顶空温度和体积的影响，以提高方法的灵敏度。优化后的程序速度很快，每次萃取仅需约 7-10 分钟，并且可以同时进行多次萃取。此外，该方法在水样中对六种紫外线过滤器表现出高精确度、良好的线性和低检测限。所开发的方法应用于池塘和湖水样品，获得了可接受的相对回收率值。
