Hunt R H
Department of Tropical Pathology, School of Pathology of the South African Institute for Medical Research, Johannesburg.
Med Vet Entomol. 1987 Jan;1(1):81-8. doi: 10.1111/j.1365-2915.1987.tb00326.x.
The use of paracentric inversions as genetic markers in the Anopheles gambiae group of mosquitoes is described. The gene for dieldrin resistance is assigned to chromosome 2 which in turn is correlated to the previous assignment of the gene to linkage group II. The locus of the enzyme phosphoglucomutase 2 (Pgm 2) is similarly assigned to chromosome 2 and evidence is presented for possible linkage between Pgm 2 and dieldrin resistance. There was no linkage or correlation of chromosome 2 and loci of the enzymes superoxide dismutase (Sod) and octanol dehydrogenase (Odh). These genes are therefore assumed to be on chromosome 3 (linkage group III). Evidence that such gene linkage group/chromosome correlations may extend to other species for which chromosome maps and homologies have been worked out is discussed.
本文描述了在冈比亚按蚊群体中使用臂内倒位作为遗传标记的情况。抗狄氏剂基因被定位到2号染色体上，这与之前将该基因定位到连锁群II的结果相关。磷酸葡萄糖变位酶2（Pgm 2）的基因座同样被定位到2号染色体上，并提供了Pgm 2与抗狄氏剂之间可能存在连锁关系的证据。2号染色体与超氧化物歧化酶（Sod）和辛醇脱氢酶（Odh）的基因座之间没有连锁或相关性。因此，这些基因被假定位于3号染色体（连锁群III）上。文中讨论了这种基因连锁群/染色体相关性可能扩展到已绘制出染色体图谱并确定同源性的其他物种的证据。
