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[蜂毒治疗后大鼠肝脏的修复性再生]

[Reparative regeneration of rat liver after treatment with bee venom].

作者信息

Zhdanova T F, Solopaeva I M, Orlov B N, Ivanova N L, Letina G A

出版信息

Arkh Anat Gistol Embriol. 1985 Jan;88(1):86-8.

PMID:2983643
Abstract

After 70% of the rat liver volume has been resected, certain stimulating effect of a single administration of bee venom (1 mg/kg) on hepatocyte proliferation is revealed. In 4 hours the amount of binuclear hepatocytes increases, and in 22-24 hours increases their mitotic activity. The effect of bee venom is explained as activation of the adenilate cyclase system by means of prostaglandins and adrenal hormones.

摘要

切除70%的大鼠肝脏体积后,单次给予蜂毒(1毫克/千克)对肝细胞增殖具有一定的刺激作用。4小时后双核肝细胞数量增加,22 - 24小时后其有丝分裂活性增强。蜂毒的作用被解释为通过前列腺素和肾上腺激素激活腺苷酸环化酶系统。

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