亨廷顿舞蹈症：4大问题。 - Suppr

Suppr

超能文献

Huntington's disease: 4 big questions.

作者信息

Nowogrodzki Anna

出版信息

Nature. 2018 May;557(7707):S48. doi: 10.1038/d41586-018-05180-3.

DOI:10.1038/d41586-018-05180-3

PMID:29844555

Abstract

摘要

相似文献

Huntington's disease: 4 big questions.

Nature. 2018 May;557(7707):S48. doi: 10.1038/d41586-018-05180-3.

How the gene behind Huntington's disease could be neutralized.

Nature. 2018 May;557(7707):S39-S41. doi: 10.1038/d41586-018-05176-z.

CRISPR takes on Huntington's disease.

Nature. 2018 May;557(7707):S42-S43. doi: 10.1038/d41586-018-05177-y.

Failure of genetic therapies for Huntington's devastates community.

Nature. 2021 May;593(7858):180. doi: 10.1038/d41586-021-01177-7.

CRISPR-Cas9 Mediated Gene-Silencing of the Mutant Huntingtin Gene in an In Vitro Model of Huntington's Disease.

Int J Mol Sci. 2017 Apr 2;18(4):754. doi: 10.3390/ijms18040754.

Improved metrics for Huntington's disease trials.

Nature. 2018 May;557(7707):S46-S47. doi: 10.1038/d41586-018-05179-w.

[Anti-sense oligonucleotides RNA therapy in Huntington disease: a great promise and many unknowns].

Med Sci (Paris). 2019 Nov;35(11):834-836. doi: 10.1051/medsci/2019165. Epub 2019 Dec 17.

Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's disease.

Sci Transl Med. 2018 Sep 12;10(458). doi: 10.1126/scitranslmed.aat7108.

Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay.

J Huntingtons Dis. 2017;6(4):349-361. doi: 10.3233/JHD-170269.

Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10809-E10818. doi: 10.1073/pnas.1705372114. Epub 2017 Nov 21.

引用本文的文献

Disruption of the mitochondrial network in a mouse model of Huntington's disease visualized by in-tissue multiscale 3D electron microscopy.

Acta Neuropathol Commun. 2024 Jun 5;12(1):88. doi: 10.1186/s40478-024-01802-2.

Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease.

Neurobiol Dis. 2024 Jun 1;195:106488. doi: 10.1016/j.nbd.2024.106488. Epub 2024 Mar 31.

The Role of the Thioredoxin System in Brain Diseases.

Antioxidants (Basel). 2022 Oct 31;11(11):2161. doi: 10.3390/antiox11112161.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Huntington's disease: 4 big questions.

作者信息

Nowogrodzki Anna

出版信息

Nature. 2018 May;557(7707):S48. doi: 10.1038/d41586-018-05180-3.

DOI:10.1038/d41586-018-05180-3

PMID:29844555

Abstract

摘要

相似文献

Huntington's disease: 4 big questions.

Nature. 2018 May;557(7707):S48. doi: 10.1038/d41586-018-05180-3.

How the gene behind Huntington's disease could be neutralized.

Nature. 2018 May;557(7707):S39-S41. doi: 10.1038/d41586-018-05176-z.

CRISPR takes on Huntington's disease.

Nature. 2018 May;557(7707):S42-S43. doi: 10.1038/d41586-018-05177-y.

Failure of genetic therapies for Huntington's devastates community.

Nature. 2021 May;593(7858):180. doi: 10.1038/d41586-021-01177-7.

CRISPR-Cas9 Mediated Gene-Silencing of the Mutant Huntingtin Gene in an In Vitro Model of Huntington's Disease.

Int J Mol Sci. 2017 Apr 2;18(4):754. doi: 10.3390/ijms18040754.

Improved metrics for Huntington's disease trials.

Nature. 2018 May;557(7707):S46-S47. doi: 10.1038/d41586-018-05179-w.

[Anti-sense oligonucleotides RNA therapy in Huntington disease: a great promise and many unknowns].

Med Sci (Paris). 2019 Nov;35(11):834-836. doi: 10.1051/medsci/2019165. Epub 2019 Dec 17.

Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington's disease.

Sci Transl Med. 2018 Sep 12;10(458). doi: 10.1126/scitranslmed.aat7108.

Validation of Ultrasensitive Mutant Huntingtin Detection in Human Cerebrospinal Fluid by Single Molecule Counting Immunoassay.

J Huntingtons Dis. 2017;6(4):349-361. doi: 10.3233/JHD-170269.

Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10809-E10818. doi: 10.1073/pnas.1705372114. Epub 2017 Nov 21.

引用本文的文献

Disruption of the mitochondrial network in a mouse model of Huntington's disease visualized by in-tissue multiscale 3D electron microscopy.

Acta Neuropathol Commun. 2024 Jun 5;12(1):88. doi: 10.1186/s40478-024-01802-2.

Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease.

Neurobiol Dis. 2024 Jun 1;195:106488. doi: 10.1016/j.nbd.2024.106488. Epub 2024 Mar 31.

The Role of the Thioredoxin System in Brain Diseases.

Antioxidants (Basel). 2022 Oct 31;11(11):2161. doi: 10.3390/antiox11112161.