Suppr超能文献

葡萄膜黑色素瘤患者的近距离放射治疗:历史回顾与未来治疗方向

Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions.

作者信息

Brewington Beatrice Y, Shao Yusra F, Davidorf Fredrick H, Cebulla Colleen M

机构信息

Havener Eye Institute, Department of Ophthalmology and Visual Science, Ohio State University.

Medical Student Research Program, The Ohio State University College of Medicine, Columbus, OH, USA.

出版信息

Clin Ophthalmol. 2018 May 17;12:925-934. doi: 10.2147/OPTH.S129645. eCollection 2018.

Abstract

Surgical management with enucleation was the primary treatment for uveal melanoma (UM) for over 100 years. The Collaborative Ocular Melanoma Study confirmed in 2001 that globe-preserving episcleral brachytherapy for UM was safe and effective, demonstrating no survival difference with enucleation. Today, brachytherapy is the most common form of radiotherapy for UM. We review the history of brachytherapy in the treatment of UM and the evolution of the procedure to incorporate fine-needle-aspiration biopsy techniques with DNA-and RNA-based genetic prognostic testing.

摘要

眼球摘除术的手术治疗是100多年来葡萄膜黑色素瘤(UM)的主要治疗方法。2001年,眼部黑色素瘤协作研究证实,对于UM,保留眼球的巩膜近距离放射治疗是安全有效的,与眼球摘除术相比,生存率无差异。如今,近距离放射治疗是UM最常见的放射治疗形式。我们回顾了近距离放射治疗在UM治疗中的历史,以及该手术的演变,以纳入基于DNA和RNA的基因预后检测的细针穿刺活检技术。

相似文献

引用本文的文献

1
Surgical treatment of uveal melanoma: Exoresection versus endoresection.葡萄膜黑色素瘤的手术治疗:外切除与内切除
Taiwan J Ophthalmol. 2025 Feb 6;15(1):34-44. doi: 10.4103/tjo.TJO-D-24-00131. eCollection 2025 Jan-Mar.
2
Innovations in brachytherapy.近距离放射治疗的创新。
Taiwan J Ophthalmol. 2025 Feb 25;15(1):62-72. doi: 10.4103/tjo.TJO-D-24-00108. eCollection 2025 Jan-Mar.
4
Proton Therapy in Uveal Melanoma.质子治疗在葡萄膜黑色素瘤中的应用
Cancers (Basel). 2024 Oct 16;16(20):3497. doi: 10.3390/cancers16203497.
6
Personalized treatment approaches in intraocular cancer.眼内癌的个性化治疗方法
Adv Ophthalmol Pract Res. 2024 Apr 13;4(3):112-119. doi: 10.1016/j.aopr.2024.03.005. eCollection 2024 Aug-Sep.

本文引用的文献

5
Germline BAP1 alterations in familial uveal melanoma.家族性葡萄膜黑色素瘤中的种系BAP1改变
Genes Chromosomes Cancer. 2017 Feb;56(2):168-174. doi: 10.1002/gcc.22424. Epub 2016 Oct 26.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验