Delnavazi Mohammad-Reza, Soleimani Maryam, Hadjiakhoondi Abbas, Yass Narguess
Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Iran J Pharm Res. 2017 Winter;16(Suppl):207-215.
(L.) Lindl. (Apiaceae) is a medicinal plant distributed in Mediterranean regions, Caucasia and southwest of Asia. In the present study phytochemical constituents of the extract obtained from the aerial parts of were investigated using various chromatographic and spectroscopic methods. Essential oil of the plant aerial parts was also analyzed using GC-MS. Five phenolic derivatives, isoimperatorin (1), ferudenol (2), caffeic acid glucosyl ester (3), isorhamnetin-3-O-β-D-glucopyranoside (4) and quercetin-3-O-β-D-glucopyranoside (5) were isolated from the aerial parts of and their structures were elucidated using H-NMR, C-NMR, EI-MS and UV spectral analyses. Twenty-seven compounds were also identified in the essential oil of plant aerial parts, of which β-pinene (43.1%), α-pinene (22.1%) and -δ3-carene (16.9%) were characterized as main compounds. The results of this study introduce as a source of potentially bioactive phenolic compounds and suggest it as an appropriate candidate for further studies.
(L.)Lindl.(伞形科)是一种分布于地中海地区、高加索地区和亚洲西南部的药用植物。在本研究中,使用各种色谱和光谱方法对从[植物名称]地上部分获得的提取物的植物化学成分进行了研究。还使用气相色谱 - 质谱联用仪(GC - MS)分析了该植物地上部分的精油。从[植物名称]地上部分分离出了五种酚类衍生物,异欧前胡素(1)、费鲁地醇(2)、咖啡酸葡萄糖酯(3)、异鼠李素 - 3 - O - β - D - 吡喃葡萄糖苷(4)和槲皮素 - 3 - O - β - D - 吡喃葡萄糖苷(5),并通过氢核磁共振(H - NMR)、碳核磁共振(C - NMR)、电子轰击质谱(EI - MS)和紫外光谱分析阐明了它们的结构。在该植物地上部分的精油中还鉴定出了27种化合物,其中β - 蒎烯(43.1%)、α - 蒎烯(22.1%)和δ3 - 蒈烯(16.9%)被确定为主要化合物。本研究结果表明[植物名称]是潜在生物活性酚类化合物的来源,并表明它是进一步研究的合适候选物。 (注:原文中多次出现未明确的植物名称,这里用[植物名称]代替)